Irina Golubeva

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Lupane C-28-imidazolides containing 3-oxo-, 3-hydroxyimino-, and 2-cyano-2,3-seco-4(23)-ene fragments in cycle A have been synthesized. 3-3-Hydroxyimino-lup-20(29)-en-28-yl-1H-imidazole-1-carboxylate showed the highest antineoplastic activity in experiments in vitro, significantly inhibiting the growth and inducing the death of cells of lung, colon cancer,(More)
Studies of mouse ear epidermis showed that proliferative activity of basal epidermal cells has two active and two passive phases throughout 24 h. Active phases consist of two subphases: long (proliferation of cambial cell descendants) and very short (cambial cell proliferation). Cambial cells proliferate at the boundary between active and passive phases;(More)
Triterpenoids with aminopropoxy groups in C-28 or C-3 and C-28 positions were synthesized from betulin, erythrodiol, uvaol, oleantriol and betulinic acid N-methylpiperazinylamide by cyanoethylation and the following catalytic hydrogenolysis. Computational estimating activity spectra of the designed compounds pointed out on their probable antineoplastic and(More)
The paper considers problems of applying information technology to the processing of ancient music manuscripts. We propose to use automated component methodology, which applies machine translation methods and allows decoding Znamenny Chants into a linear notation. The present work describes basic stages of the methodology. In order to implement the(More)
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