Irina A Sokolova

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The reversible aggregation of red blood cells (RBCs) continues to be of the basic science and clinical interest. Recently it has been reported about a specific binding between fibrinogen and unknown erythrocyte glycoprotein receptors. The aim of this study was to investigate whether the red blood cell aggregation (RBCA) include the cell-cell interaction(More)
The paper gives the results of sequence analysis of 150 positive samples in real-time RT-PCR, including 47 autopsy materials from patients (including 10 pregnant women), who died from fatal pneumonia mainly in November-December 2009, in whom the lifetime etiological diagnosis had not been made and hence no early etiotropic therapy performed. 70% of the(More)
There are complex interactions between blood cells, and erythrocytes may enhance platelet aggregation. However, there is a lack of information about the influence of platelets on RBC rheological properties and RBC (dis)aggregation. The purpose of this study was to investigate the process of RBC (dis)aggregation in conditions of inhibition of fibrinogen(More)
Direct measurements of aggregation forces in piconewton range between two red blood cells in pair rouleau are performed under physiological conditions using double trap optical tweezers. Aggregation and disaggregation properties of healthy and pathologic (system lupus erythematosis) blood samples are analyzed. Strong difference in aggregation speed and(More)
Interpretation of the results of chromatin fragmentation by nucleases is usually based on analysis of the distribution of the sizes and numbers of DNA and DNP fragments on electrophoresis in agarose and polyacrylamide gels or during centrifugation in density gradients. Better fractionation is achieved by electrophoresis, although in this case quantitative(More)
The presence of a whole series of endonuclease activities has been demonstrated in animal tissue cell nuclei [i0]. The causes of their diversity and their presence in cell nuclei have not yet been explained. Attention has been drawn to the fact that one particular endonuclease, whose properties are similar in different tissues of the body and in different(More)
242 cases of brain arterio-venous malformations (AVM) are analysed clinically and anatomically. Their pathology, histological, ultrastructural and immunohistochemical characteristics, therapeutic pathomorphosis are described. The concept is suggested according to which AVM is a collective term including true developmental defects, dysembryogenetic tumors(More)
The observation of stromal gastric tumor of 12 years old girl has been investigated. The diagnostics was carried out on tumor biopsy taken by a laparoscopy. An evident edema of stroma caused "pseudo-papillary" organization of epithelioid cell neoplasm prevented the right diagnosis established only by immunohistochemical staining of CD117 and CD34 markers.(More)
AIM to define the clinical value of changes in blood rheological properties and renal endothelial function in patients with hematuric and nephritic forms of chronic glomerulonephritis (CGN) and to ascertain whether the indices under study can be applied to assess the activity (progression) of nephritis and used as a prognostic criteria. SUBJECTS AND(More)