Irfan Pervaiz

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For centuries microbial biotransformation has proved to be an imperative tool in alleviating the production of various chemicals used in food, pharmaceutical, agrochemical and other industries. In the field of pharmaceutical research and development, biotransformation studies have been extensively applied to investigate the metabolism of compounds (leads,(More)
For centuries microbial biotransformation has proved to be an imperative tool in alleviating the production of various chemicals used in food, pharmaceutical, agrochemical and other industries. In the field of phar- maceutical research and development, biotransformation studies have been extensively applied to investigate the metabolism of compounds (leads,(More)
In the present research, the steroidal anti-asthmatic drug beclomethasone dipropionate was subjected to microbial biotransformation by Aspergillus niger. Beclomethasone dipropionate was transformed into various metabolites first time from microbial transformation. New drug metabolites produced can act as new potential drug molecules and can replace the old(More)
This article reports microbial biotransformation of dexamethasone, a synthetic glucocorticoid, by Bacillus subtilis. This bacterium can be used as a microbial metabolic model to investigate the metabolism of other synthetic glucocorticoids as it mimics mammalian metabolism to a certain extent. Incubation of dexamethasone with B. subtilis for 7 days yielded(More)
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