Irfan Newaz Khan

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Atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed xin blood vessels. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations have been used(More)
The present study was carried out to evaluate both the ethanol and water extracts of entire plant Euphorbia hirta (Family: Euphorbiaceae) for its anti-diarrheal potential against some of the experimental model of diarrhea in rats. The plant showed significant inhibitatory activity against castor-oil-induced diarrhea and PGE2 induced enteropooling in rats.(More)
OBJECTIVE To evaluate possible anxiogenic activity, sedative property and anxiolytic potential of crude ethanolic extract of Calotropis gigantea leaves. METHODS The anxiogenic activity of crude ethanolic extract of Calotropis gigantea leaves was evaluated using standard animal behavioral models, such as hole cross and open field; sedative property and(More)
An in-vitro thrombolytic model was used to check the clot lysis effect of four herbal extracts viz., Honey, Nigella sativa, Capsicum frutescens, Brassica oleracea, combination of Honey & Nigella sativa and Honey & Capsicum frutescens along with Streptokinase as a positive control and water as a negative control. And also brine shrimp lethality bio-assay was(More)
The present study was designed to develop a suitable matrix type transdermal drug delivery system (TDDS) of domperidone maleate using blends of three different polymeric combinations of polyvinylpyrrolidone (PVP) and ethylcellulose (EC). Physical studies including moisture content, moisture uptake and flatness to study the stability of the formulations were(More)
A model is developed to predict the precipitation kinetics and strengthening in Al–Cu–Mg alloys during non-isothermal treatments consisting of controlled heating and cooling. The prediction of the precipitation kinetics is based on the Kampmann and Wagner model. The precipitation strengthening by the shearable Cu–Mg co-clusters is modelled on the basis of(More)
The present work applies a model for microstructural evolution in the solid state and Al–Cu–Mg alloys and expands it in a computationally efficient way to include solid–liquid reactions in fusion welds. The model is used to predict local strength and hardness of the welds, using a formulation that incorporates hardening due to two types of precipitates,(More)
In this study, the ethanol extract of Cissampelos pareira has been evaluated. The extract was tested for analgesic properties using both hot plate and acetic acid-induced writhing methods. Antiinflammatory effect was investigated using two different doses of 250 and 500 mg/kg body weight on Evans rats by carrageenan-induced paw edema test. The antipyretic(More)
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