Irene Z Wang

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PURPOSE Fast ripples are reported to be highly localizing to the epileptogenic or seizure-onset zone (SOZ) but may not be readily found in neocortical epilepsy, whereas ripples are insufficiently localizing. Herein we classified interictal neocortical ripples by associated characteristics to identify a subtype that may help to localize the SOZ in(More)
The last step of cell division, cytokinesis, produces two daughter cells that remain connected by an intercellular bridge. This state often represents the longest stage of the division process. Severing the bridge (abscission) requires a well-described series of molecular events, but the trigger for abscission remains unknown. We found that pulling forces(More)
Heat shock triggers a transient and ubiquitous response, the function of which is to protect cells against stress-induced damage. The heat-shock response is controlled by a key transcription factor known as heat shock factor 1 (HSF1). We have developed a multiconfocal fluorescence correlation spectroscopy setup to measure the dynamics of HSF1 during the(More)
Determining the number of fluorescent entities that are coupled to a given molecule (DNA, protein, etc.) is a key point of numerous biological studies, especially those based on a single molecule approach. Reliable methods are important, in this context, not only to characterize the labeling process but also to quantify interactions, for instance within(More)
PURPOSE There have been an increasing number of studies involving ultra-high-field 7T of intracranial pathology, however, comprehensive clinical studies of neuropathology at 7T still remain limited. 7T has the advantage of a higher signal-to-noise ratio and a higher contrast-to-noise ratio, compared to current low field clinical MR scanners. We hypothesized(More)
PURPOSE OF REVIEW Advanced MRI postprocessing techniques are increasingly used to complement visual analysis and elucidate structural epileptogenic lesions. This review summarizes recent developments in MRI postprocessing in the context of epilepsy presurgical evaluation, with the focus on patients with unremarkable MRI by visual analysis (i.e.(More)
From 377 consecutive MEG studies for patients with intractable epilepsy performed at the Cleveland Clinic between 2008 and 2011, 19 patients were referred for a repeat MEG. Source localization was done using a single equivalent current dipole (ECD) model on identified interictal spike activity. Clinical, neuroimaging, and concurrent EEG and MEG findings(More)
Thèse dirigée par Antoine Delon et codirigée par Irène Wang préparée au sein du Laboratoire interdisciplinaire de Physique dans le cadre de l' Ecole Doctorale de Physique, Grenoble Multi-confocal fluorescence correlation spectroscopy and its application to the study of the cellular response to heat shock Thèse soutenue publiquement le 1er octobre 2012 ,(More)
The views in this paper are solely the responsibility of the authors and should not be interpreted as reflecting the views of the Federal Reserve Bank of San Francisco or the Board of Governors of the Federal Reserve System. Abstract Under the strong-form of market discipline, publicly traded banks that have constantly available public market signals from(More)
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