Irene S. Alexander

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The use of large doses of methotrexate (MTX), greater than 3 g/m2, for the treatment of some malignant disorders requires careful monitoring of serum concentrations. A simple and sensitive method for the separation of MTX and 7-hydroxymethotrexate (7-OH-MTX) by reversed-phase high-performance liquid chromatography (HPLC) is described. The method involves(More)
and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation. Abstract We investigated human interaction with a specific telerobotic installation: The Telegarden, a community garden that allows users to plant and tend seeds in a remote garden by controlling(More)
Acute experimental synovitis was produced by intra-articular challenge of 3 baboons (Papio cynocephalus) sensitised with ovalbumin. Haemagglutination tests revealed high titres of circulating antiovalbumin antibody. Measurements were made of articular diameter, circumference, and temperature before the animals were killed on days 1, 5, and 20. The sterile(More)
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