Irene Papanicolaou

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A potent anti-vascular endothelial growth factor (VEGF) biologic and a compatible delivery system were co-evaluated for protection against wet age-related macular degeneration (AMD) over a 6month period following a single intravitreal (IVT) injection. The anti-VEGF molecule is dimeric, containing two different anti-VEGF domain antibodies (dAb) attached to a(More)
Inflammatory bowel diseases (IBD) include a variety of intestinal disorders, widely distributed throughout the human population. In recent years Nitric Oxide (NO) has been shown to play a role in the pathophysiology of IBD both in patients and in animal models. The aim of this study was to examine the effect of L-arginine on the inflammatory response(More)
After a brief reference to the ordinary use of the "Komarov" mesogenic vaccinal strain of Newcastle disease virus for the secondary vaccination of domestic fowls, the authors deal with laboratory experiments conducted to ascertain that this strain can be used for the same purpose by the drinking water method. Three groups of chickens 45 days old(More)
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