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- Stephanie Ma, Kwok-wah Chan, +5 authors Xinyuan Guan
- Gastroenterology
- 2007
BACKGROUND & AIMS
Recent efforts in stem cell biology suggest that tumors are organized in a hierarchy of heterogeneous cell populations and that the capability to maintain tumor formation/growth… (More)
- Wanling Yang, Nan Shen, +28 authors Yu Lung Lau
- PLoS genetics
- 2010
Systemic lupus erythematosus is a complex and potentially fatal autoimmune disease, characterized by autoantibody production and multi-organ damage. By a genome-wide association study (320 patients… (More)
- Terence Kin-Wah Lee, Antonia Castilho, Vincent Chi Ho Cheung, Kwan Ho Tang, Stephanie Ma, Irene Oi-lin Ng
- Cell stem cell
- 2011
Tumor-initiating cells (T-ICs) are a subpopulation of chemoresistant tumor cells that have been shown to cause tumor recurrence upon chemotherapy. Identification of T-ICs and their related pathways… (More)
- Timothy M Pawlik, Keith A. Delman, +8 authors Eddie K. Abdalla
- Liver transplantation : official publication of…
- 2005
Vascular invasion and high histologic grade predict poor outcome after surgical resection or liver transplantation for hepatocellular carcinoma (HCC). Despite the known association between tumor size… (More)
- Sandy Leung-Kuen Au, Carmen Chak-lui Wong, +4 authors Chun-Ming Wong
- Hepatology
- 2012
UNLABELLED
Epigenetic alterations and microRNA (miRNA) deregulation are common in hepatocellular carcinoma (HCC). The histone H3 lysine 27 (H3K27) tri-methylating enzyme, enhancer of zeste homolog 2… (More)
- Chun-Ming Wong, Judy Wai-Ping Yam, +4 authors Irene Oi-lin Ng
- Cancer research
- 2005
Deleted in liver cancer (DLC1) is a candidate tumor suppressor gene recently isolated from human hepatocellular carcinoma. Structurally, DLC1 protein contains a conserved GTPase-activating protein… (More)
- Chun-Ming Wong, Joyce M. Lee, Yick Pang Ching, Dong-Yan Jin, Irene Oi-lin Ng
- Cancer research
- 2003
Hepatocellular carcinoma (HCC) is one of the most common fatal cancers in the world. However, the underlying molecular mechanisms contributing to hepatocarcinogenesis are still unclear. A putative… (More)
- Stephanie Ma, Kwan Ho Tang, +12 authors Xinyuan Guan
- Cell stem cell
- 2010
A novel paradigm in tumor biology suggests that cancer growth is driven by stem-like cells within a tumor, called tumor-initiating cells (TICs) or cancer stem cells (CSCs). Here we describe the… (More)
- Chung-Mau Lo, Chi Leung Liu, +5 authors John Wong
- Annals of surgery
- 2007
OBJECTIVE
We conducted a randomized controlled trial of adjuvant interferon therapy in patients with predominantly hepatitis B-related hepatocellular carcinoma (HCC) to investigate whether the… (More)
- Judy Wai Ping Yam, Frankie Chi Fat Ko, C Chan, Dong-Yan Jin, Irene Oi-lin Ng
- Cancer research
- 2006
Deleted in liver cancer 1 (DLC1) is a recently identified tumor suppressor gene frequently underexpressed in hepatocellular carcinoma (HCC). DLC1 encodes a Rho GTPase-activating protein domain that… (More)