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Validated Risk Score for Predicting 6‐Month Mortality in Infective Endocarditis
Background Host factors and complications have been associated with higher mortality in infective endocarditis (IE). We sought to develop and validate a model of clinical characteristics to predictExpand
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Predicting the occurrence of embolic events: an analysis of 1456 episodes of infective endocarditis from the Italian Study on Endocarditis (SEI)
BackgroundEmbolic events are a major cause of morbidity and mortality in patients with infective endocarditis. We analyzed the database of the prospective cohort study SEI in order to identifyExpand
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Safety of treatment with high-dose daptomycin in 102 patients with infective endocarditis.
Daptomycin is commonly used at doses >6 mg/kg/day for various indications, including infective endocarditis (IE). A systematic assessment of skeletal muscle, renal, haematological, hepatic andExpand
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Pneumonia and hospitalizations in the elderly
Pneumonia in the elderly is a common and severe problem. In this review we analyze the state of the art for pneumonia in the elderly. Several aspects are discussed: i) how common is the disease;Expand
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High-dose daptomycin for cardiac implantable electronic device-related infective endocarditis.
BACKGROUND Cardiac implantable electronic device (CIED)-related endocarditis is a growing challenge because of increasing incidence and significant mortality. Current treatment is based on completeExpand
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Current trends in the management of cardiac implantable electronic device (CIED) infections
Cardiac implantable electronic device (CIED) infections are an emerging clinical problem. A growing number of dedicated and high quality clinical studies are currently being generated. We here reviewExpand
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Lipid Accumulation in Hearts Transplanted From Nondiabetic Donors to Diabetic Recipients.
BACKGROUND Early pathogenesis of diabetic cardiomyopathy (DMCM) may involve lipotoxicity of cardiomyocytes in the context of hyperglycemia. There are many preclinical studies of DMCM pathogenesis,Expand
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Infective endocarditis due to multidrug resistant gram-negative bacilli: single centre experience over 5 years.
BACKGROUND Infective endocarditis (IE) due to gram-negative (GN) bacilli is uncommon. Although multi- and extensively-drug resistant (MDR/XDR) GN infections are emerging, very few data are availableExpand
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Clinical significance of hyperhomocysteinemia in infective endocarditis
AbstractBlood coagulation plays a key role in the pathogenesis of infective endocarditis (IE). Conditions associated with thrombophilia could enhance IE vegetation formation and promote embolicExpand
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Sacubitril/valsartan in patients listed for heart transplantation: effect on physical frailty†
The aim of this study was to investigate prospectively the effect of sacubitril/valsartan in advanced heart failure (HF) patients in waiting list for heart transplantation (HT) and the effect onExpand
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