Irene Higginson

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OBJECTIVES To determine the relative influence of different factors on place of death in patients with cancer. DATA SOURCES Four electronic databases-Medline (1966-2004), PsycINFO (1972-2004), CINAHL (1982-2004), and ASSIA (1987-2004); previous contacts with key experts; hand search of six relevant journals. REVIEW METHODS We generated a conceptual(More)
Objectives—To develop an outcome measure for patients with advanced cancer and their families which would cover more than either physical symptoms or quality of life related questions. To validate the measure in various specialist and nonspecialist palliative care settings throughout the UK. Design—A systematic literature review of measures appropriate for(More)
Little attention has been paid to the symptom management needs of patients with life-threatening diseases other than cancer. In this study, we aimed to determine to what extent patients with progressive chronic diseases have similar symptom profiles. A systematic search of medical databases (MEDLINE, EMBASE, and PsycINFO) and textbooks identified 64(More)
To determine whether hospital-based palliative care teams improve the process or outcomes of care for patients and families at the end of life, a systematic literature review was performed employing a qualitative meta-synthesis and quantitative meta-analysis. Ten databases were searched. This was augmented by hand searching specific journals, contacting(More)
BACKGROUND Numbers of patients with stage 5 chronic kidney disease (CKD) managed conservatively (without dialysis) are increasing steadily but prevalence and severity of symptoms in this population are not yet known. AIM To describe symptom prevalence, symptom severity, and total symptom burden in patients with stage 5 CKD managed conservatively. METHOD(More)
BACKGROUND HoNOSCA (Health of the Nation Outcome Scales for Children and Adolescents) is a recently developed measure of outcome for use in child and adolescent mental health services (CAMHS). AIMS To examine HoNOSCA's sensitivity to change, convergent validity and clinical usefulness. METHOD Prospective study of new CAMHS attenders. Questionnaires(More)
BACKGROUND Home-based models of hospice and palliative care are promoted with the argument that most people prefer to die at home. We examined the heterogeneity in preferences for home death and explored, for the first time, changes of preference with illness progression. METHODS We searched for studies on adult preferences for place of care at the end of(More)
CONTEXT Palliative care is being advocated for noncancer patients but needs evidence of effectiveness and cost-effectiveness. OBJECTIVE We evaluated the cost-effectiveness of a new palliative care service for people with multiple sclerosis (MS). METHODS We used a randomized fast-track Phase II controlled trial. Patients in South East London who were(More)