Irene Braithwaite

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OBJECTIVE To investigate whether antibiotic exposure during the first year of life is associated with increased childhood body mass index (BMI). DESIGN Secondary analysis from a multi-centre, multi-country, cross-sectional study (The International Study of Asthma and Allergies in Childhood Phase Three). SUBJECTS A total of 74 946 children from 31(More)
BACKGROUND Studies exploring the effect of television viewing on obesity throughout childhood are conflicting. Most studies have been confined to single high-income countries. Our aim was to examine the association between television viewing habits and Body Mass Index (BMI) in adolescents and children in a multicentre worldwide sample. METHODS In the(More)
BACKGROUND The clinical utility of serum periostin as a type 2 biomarker in asthma is limited by lack of reference range values derived from a population without respiratory disease. OBJECTIVE To derive age- and sex-related reference intervals for serum periostin from an adult population without asthma or COPD. METHODS Serum periostin levels were(More)
BACKGROUND There is non-experimental evidence that paracetamol (acetaminophen) use may increase the risk of developing asthma. However, numerous methodological issues need to be resolved before undertaking a randomized controlled trial to investigate this hypothesis. OBJECTIVE To establish the feasibility of a randomized controlled trial of liberal(More)
BACKGROUND Breastfeeding is believed to reduce children's risk for obesity but data are conflicting. It is also uncertain if breastfeeding has different effects on obesity in high- and low-income countries. OBJECTIVES This study aimed to investigate the association between having been breastfed and body mass index (BMI) in 6- to 7-year-old children in a(More)
OBJECTIVE To investigate whether reported fast-food consumption over the previous year is associated with higher childhood or adolescent body mass index (BMI). DESIGN Secondary analysis from a multicentre, multicountry cross-sectional study (International Study of Asthma and Allergies in Children (ISAAC) Phase Three). SUBJECTS AND METHODS(More)
BACKGROUND Patterns of inhaled β2-agonist therapy use during severe asthma exacerbations before hospital attendance are poorly understood. AIMS To assess β2-agonist use prior to hospital attendance. METHODS We undertook an exploratory post hoc analysis of data from a 6-month clinical trial of 303 patients randomised to combination budesonide/formoterol(More)
Background. A novel, micromobile foot compression device (MMC) has been developed to reduce the risk of venous thromboembolism associated with prolonged seated immobility. Objective. To compare the efficacy of the MMC with graduated compression stockings in augmenting lower limb venous blood flow. Patients/Methods. Twenty participants were randomised to(More)
Serum periostin is a potential biomarker of response to therapies that target type 2 inflammation in asthma. The objectives of this study were to describe: 1) the distribution of serum periostin levels in adults with symptomatic airflow obstruction; 2) its relationship with other variables, including type 2 biomarkers; and 3) the effect of inhaled(More)
OBJECTIVE To investigate the efficacy of topical 90% medical-grade kanuka honey and 10% glycerine (Honevo) as a treatment for rosacea. DESIGN Randomised controlled trial with blinded assessment of primary outcome variable. SETTING Outpatient primary healthcare population from 5 New Zealand sites. PARTICIPANTS 138 adults aged ≥ 16, with a diagnosis of(More)