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Oxidative stress plays a role in the light damage model of retinal degeneration as well as in age-related macular degeneration. The purpose of this study is to identify retinal genes induced by acute photo-oxidative stress, which may function as mediators of apoptosis or as survival factors. To accomplish this, Balb/c mice were exposed to bright cool white(More)
PURPOSE To explore the association of angiographic nonperfusion with anterior segment and posterior segment neovascularization in central retinal vein occlusion (CRVO). METHODS An imaging database at one institution was searched for the diagnosis of central retinal vein occlusion. Ultra wide field fluorescein angiograms were graded for image quality, the(More)
Eyes with implanted hardware carry a higher risk of infection. Here we report a rare case of Nocardia farcinica endophthalmitis and Baerveldt implant infection originating from infectious keratitis in a patient with a Boston type I keratoprosthesis. The infection resolved with aggressive surgical and medical treatment.
BACKGROUND Vitrectomy systems are now available with 20-, 23-, and 25-gauge vitreous cutters and are designed to be used with conventional or new generation pneumatic actuation technology. METHODS Five vitreous cutters using pneumatic actuation technology were studied. Flow rates were evaluated using porcine vitreous. A high-speed camera timed the cutting(More)
Diabetic macular edema (DME) is the most common cause of vision loss in patients with type 1 and type 2 diabetes. Glycemic control, hypertension, and dyslipidemia are known to be important risks factors for DME. In addition, nephropathy, anemia, sleep apnea, glitazone usage, and pregnancy are also important modifiable risk factors. It is important for(More)
AIM To describe a subset of patients with recurrent retinal detachments caused by anterior intraretinal and subretinal proliferative vitreoretinopathy (PVR), which required greater than 180 degrees retinotomy and silicone oil tamponade. METHODS Interventional case series. Forty-one patients underwent >180 degrees retinotomy, anterior retinectomy, removal(More)
Primary scleral buckling has been an effective means to reattach the retina for over 50 years. After surgery, complications may arise that require scleral buckle (SB) removal. The most common indications for SB removal are extrusion, infection, and pain. I review the pertinent literature in an effort to develop guidelines for when to remove a SB.
PURPOSE Uveitis can occur in all segments of the eye and has multiple etiologies, (many of which remain poorly understood). Appropriate diagnosis and subsequent management can depend on elucidation of the clinical signs. Many diagnostic features are often best identified with Fluorescein angiography. However these signs are often peripheral and(More)
INTRODUCTION Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the developing retina and a significant cause of childhood blindness around the world. Vascular endothelial growth factor (VEGF) plays an important role in the neovascular phase of ROP, and treatment with an anti-VEGF agent is justified in select cases. Bevacizumab is the most(More)