Irena Daniszewska

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Objective. This study evaluated oxidative damage caused to the salivary glands in streptozotocin-induced diabetes (DM). Materials and Methods. Rats were divided into 4 groups: groups 1 and 2, control rats, and groups 3 and 4, DM rats. 8-Hydroxy-2'-deoxyguanosine (8-OHdG), protein carbonyl (PC), 4-hydroxynonenal protein adduct (4-HNE), oxidized and/or(More)
The aim of the present study was to investigate the correlation between ultrastructural changes of the liver and lung, intensity of lipid peroxidation (measured by the level of malondialdehyde (MDA)) in liver and lung tissue homogenates and the alterations in the activities of superoxide dismutase (Cu,Zn-SOD) and glutathione reductase (GSSG-R) following(More)
Matrix metalloproteinases (MMPs) belong to a family of structurally related zinc-dependent proteolytic enzymes that are known to play a key role in the catabolic turnover of extracellular matrix (ECM) components. Research studies to date have indicated that MMPs regulate the activity of several non-ECM bioactive substrates, including growth factors,(More)
Sjögren's syndrome (SS--Sjögren's Syndrom) is an autoimmune systemic disease of connective tissue. The aim of this study was to present the contemporary literature on the basis of the pathophysiology of the Sjögren's syndrome, with particular reference to the pathogenesis of the damage to the salivary glands. It also discusses the criteria for(More)
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