Irela Gretchen Reza Mazar

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UNLABELLED Activation of the renin angiotensin system resulting in stimulation of angiotensin-II (AngII) type I receptor (AT1R) is an important factor in the development of liver fibrosis. Here, we investigated the role of Janus kinase 2 (JAK2) as a newly described intracellular effector of AT1R in mediating liver fibrosis. Fibrotic liver samples from(More)
Hepatic myofibroblasts (MFB) show increased proliferation, migration and collagen production, which are crucial for hepatic fibrogenesis. Atorvastatin treatment inhibits proliferation, apoptosis and cytokine production of MFB in bile duct-ligated (BDL) rats in vivo. Here, we have further investigated the underlying mechanisms. Primary rat hepatic stellate(More)
To gain a better understanding of factors which determine the effectiveness, efficiency and sustainability of community-based food and nutrition programmes, FAO has developed a conceptual framework and methodology to analyze these programmes. Based on selection criteria, 9 case studies were carried out in Latin America, Africa and Asia. The success factors(More)
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