Iqwal Mangat

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OBJECTIVE This study investigated gender differences, depression, and health-related quality of life (QoL) in a cross-sectional sample of patients with atrial fibrillation (AF). METHODS This cross-sectional study involved a convenience sample of AF patients from two tertiary-care clinics in Toronto, Canada. Ninety-three AF patients completed(More)
BACKGROUND Abnormal intercellular communication caused by connexin dysfunction may contribute to atrial fibrillation (AF). The present study assessed the effect of the gap junction conduction-enhancing antiarrhythmic peptide GAP-134 on AF inducibility and maintenance in a dog model of atrial cardiomyopathy. METHODS AND RESULTS Twenty-four dogs subject to(More)
BACKGROUND A conceptualized model may be useful for understanding risk stratification of primary prevention implantable cardioverter defibrillators considering the competing risks of appropriate implantable cardioverter defibrillator shock versus mortality. METHODS AND RESULTS In a prospective, multicenter, population-based cohort with left ventricular(More)
BACKGROUND For the primary prevention of sudden cardiac death, guidelines provide left ventricular ejection fraction (EF) criteria for implantable cardioverter defibrillator (ICD) placement without specifying the technique by which it should be measured. We sought to investigate the potential impact of performing cardiovascular magnetic resonance (CMR) for(More)
BACKGROUND Epidemiological studies have assessed T-wave alternans (TWA) as a possible mechanism of cardiac arrhythmias related to air pollution in high-risk subjects and have reported associations with increased TWA magnitude. OBJECTIVE In this controlled human exposure study, we assessed the impact of exposure to concentrated ambient particulate matter(More)
Le syndrome métabolique est devenu un problème médical fréquemment débattu et un sujet d'intérêt croissant pour les chercheurs et l'industrie pharmaceutique. Dans ce numéro de Cardiologie – Conférences scientifiques, nous examinons le concept de syndrome métabolique et les diverses définitions utilisées pour le diagnostiquer et nous décrivons les facteurs(More)
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