Iqbal Mustafa

Learn More
Most physicians involved in intensive care consider lactate solely as a deleterious metabolite, responsible for high morbidity and bad prognosis in severe patients. For the physiologist, however, lactate is a key metabolite, alternatively produced or consumed. Many studies in the literature have infused animals or humans with exogenous lactate,(More)
Although hypertonic saline has been proposed as an intravenous resuscitation fluid, the beneficial effects of the sodium load are associated with potentially deleterious effects of chloride. Since the physiological lactate anion is well metabolized, hypertonic lactate solution could represent an interesting alternative. The aim of this study was to compare(More)
To compare two solutions for fluid resuscitation in post-coronary artery bypass grafting (CABG) surgery patients: Ringer’s lactate (RL) versus a new solution containing half-molar sodium-lactate (HL). Prospective randomized open label study. The first 12 h post-CABG surgery in an intensive care unit (ICU). There were 230 patients enrolled in the study: 208(More)
We have investigated the role of cardiopulmonary bypass on lactate metabolism in patients undergoing uncomplicated surgery for elective coronary artery bypass grafting (CABG). Prospective non-randomized observational study. National Cardiovascular Center. Three independent groups were studied: preoperative (n=20), postoperative with bypass (CPB, n=20) and(More)
PURPOSE OF REVIEW Cardiovascular disease is one of the most important causes of morbidity and mortality in western countries, generating an increasing number of admissions to intensive care units. Cardiac failure has long been associated with nutritional disorders, malnutrition and cachexia being frequent during the late phases of congestive heart failure:(More)
Lactate is a key metabolite that is produced by every cell and oxidized by most of them, provided that they do contain mitochondria. Its metabolism is connected to energetic homeostasis and the cellular redox state. It is well recognized as an indicator of severe outcome in severely ill patients, however, it is not a detrimental factor per se. Conversely,(More)
The rapid economic, scientific, and technologic development in Asia probably is the most important in the world today. Eventually, the development of health care and critical care medicine in the Western Pacific will be affected. Even with the problems that have to be faced, the future of critical care medicine in the region looks promising.However, the(More)
Mycophages were successfully isolated from lysogenic bovine strains without previous exposure to physical or chemical agents. These mycophages were exposed to 53 mycobacterial strains using ATCC 607 as an indicator strain. These strains included rapidly growing strains, human, bovine, avian, murine and BCG strains of different geographical origin.(More)
P 156 DEVELOPMENT OF LOCULATED PLEURAL BLOOD DURING ECLS AND TREATMENT WITH UROICINASE. Montgomery VL'Eberly SM. University of Louisville, Kosair Children's Hospital, Louisville, KY. A 5 year old African-American child suffered a severe pulmonary injury in a house fire. Initial survey revealed 1 % total body surface burns, soot on the face, and bloody(More)
  • 1