Ipek Guler

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Treatment of phenylketonuria involves a restriction in the intake of natural proteins. This can lead to growth impairment. Weight, height and body mass index of 109 hyperphenylalaninemic patients (mild hyperphenylalaninemia (HPA) and phenylketonuria (PKU)) were determined from birth until 18 years, every 6 months, and differences to the healthy population,(More)
In many follow-up studies different types of outcomes are collected including longitudinal measurements and time-to-event outcomes. Commonly, it is of interest to study the association between them. Joint modeling approaches of a single longitudinal outcome and survival process have recently gained increasing attention from both frequentist and Bayesian(More)
A common objective in follow-up studies is to characterize the relationship between longitudinal measurements and time-to-event outcomes. For this aim, various methods were proposed in the statistical literature, such as an extended version of the Cox model with longitudinal covariates or a two-stage approach. However, these techniques have several(More)
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