Iolanda E. Low

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Low, Iolanda E. (Harvard Medical School, Boston, Mass.), and Monroe D. Eaton. Replication of Mycoplasma pneumoniae in broth culture. J. Bacteriol. 89:725-728. 1965.-Reproducible growth curves of Mycoplasma pneumoniae can be obtained with the use of shaking cultures, which allows earlier and higher yields of the organism than stationary or roller cultures.(More)
Cell-free extracts of Mycoplasma pneumoniae showed two distinct reduced nicotinamide adenine dinucleotide (NADH(2)) oxidase activities in the supernatant fraction. By ammonium sulfate fractionation and polyacrylamide gel electrophoresis, one activity not requiring flavine co-factors was precipitated by 50 to 70% ammonium sulfate concentration and identified(More)
No catalase activity was detected in four strains of glucose-grown Mycoplasma pneumoniae at any time during the replication of the organism. Exogenous catalase dramatically increased the O(2) uptake with glycerol, presumably by releasing inhibition caused by hydrogen peroxide. The effect of added catalase on the O(2) uptake of washed organisms with glucose(More)
Four amino acids, lysine, leucine, tryptophane, and phenylalanine, at concentrations of 0.5 to 5.0 mg./ml. inhibit the production of influenza viral hemagglutinins and complement-fixing S antigen in Krebs 2 ascites cells suspended in a medium containing only glucose and glutamate as substrates. In Krebs 2 cells no new infectious virus is formed but the(More)
A mycoplasmacidal system consisting of myeloperoxidase (MPO)-containing granules, H(2)O(2), and a halide is described. In all parameters measured, it appears to be identical to the MPO-H(2)O(2)-halide bactericidal system previously reported. It has a pH optimum of approximately 5.5 and an optimal MPO:H(2)O(2) ratio of 1:25. The halide requirement can be(More)
H(2)O(2) levels accumulated by Mycoplasma pneumoniae can be influenced by carbon source, different horse sera, yeast extract, thallium acetate, or growth in a simplified, dialyzed medium. Thus, increased levels of H(2)O(2) were detected by growth in glycerol, by omission of thallium acetate, and by the use of dialyzed medium. The ability of M. pneumoniae in(More)