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The effects of the CYP3A4 inducer, Hypericum perforatum, on the pharmacokinetics of a single oral dose of ivabradine were assessed. An open-label, 2-period, nonrandomized, phase-I, pharmacokinetic… (More)
In vivo preventive effects of a Mangifera indica L extract (Vimang) or its major component mangiferin on iron overload injury have been studied in rats given respectively, 50, 100, 250 mg kg(-1) body… (More)
ETHNOPHARMACOLOGICAL RELEVANCE Heliopsis longipes (A. Gray) Blake (Asteraceae) is a broadly used species in the Mexican, Central and South American Traditional Medicine for its anaesthetic,… (More)
SUMMARY. This study examines the anti-inflammatory activity of some species of Zanthoxylum genus. We evaluated 4 ethanolic extracts from stem bark of Zanthoxylum elephantiasis Macfd., Z. fagara (L.)… (More)
Resumen Context: Herbal drugs are a mixture of active compounds and the chemical complexity of each formulation increase with the possibility of interactions between them and conventional drugs. Many… (More)
Central sensitization theory has been defined as pivotal for understanding the excitability changes in central neurons following peripheral inflammation or neuropathic injury. Considerable evidence… (More)