Ioan Brebenel

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CONTEXT Cardiopulmonary bypass (CPB) is a commonly used technique in cardiac surgery but is associated with acute, transient, renal dysfunction that has a negative impact on long-term survival. OBJECTIVE To unravel the molecular pathogenesis of renal injury following CPB. DESIGN To obtain insight into the pathogenesis of renal dysfunction following CPB,(More)
microarray analysis of gene expression profiles in the kidney demonstrates a local inflammatory response induced by cardiopulmonary bypass in the rat 41 mmHg, and arterial blood gas analysis), with O2/air (1:2) at a ventilation rate of 50 min-1 (0.5 s inspiration time). Rectal temperature was kept at 37.0 ± 0.5 °C, using an electrical heating pad. The left(More)
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