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OBJECTIVE To assess the efficacy and safety of the topical 5% lidocaine medicated plaster in the treatment of localized neuropathic pain. STUDY DESIGN This was a case series at an Austrian pain clinic, using retrospective analysis. PATIENTS AND METHODS Data of 27 patients treated for localized neuropathic pain with the 5% lidocaine medicated plaster(More)
BACKGROUND In 2001, a transdermal matrix patch formulation of buprenorphine was approved for the treatment of moderate to severe cancer pain and severe pain that is unresponsive to nonopioid analgesics. The primary recommendation contained in the prescribing information was that transdermal patches be worn for a 3-day period before application of a new(More)
BACKGROUND Tramadol is widely prescribed, even to the eldest patients. Although age-related differences in pharmacologic responsiveness are to be expected, the pharmacodynamic and pharmacokinetic (PK) properties of tramadol have not been systematically compared between patients of various ages. OBJECTIVE The aim of this study was to explore the(More)
Activation of opioid receptors on peripheral sensory nerve terminals by opioid peptides that are produced and released from immune cells can result in inhibition of inflammatory pain. This study tests the hypothesis that postoperative pain is attenuated endogenously through a local sympathetic neurotransmitter-activated release of opioids in patients(More)
AIM The aim of this study was to determine whether P-STIM-verum in patients undergoing laparoscopic nephrectomies resulted in a lower consumption of analgesics and an improvement of pain scores compared with P-STIM-placebo when administered for acute peri- and postperative pain. METHODS The study was carried out in a double-blind, randomized, controlled(More)
OBJECTIVES To compare the efficacy and tolerability of transdermal buprenorphine in elderly patients and 2 younger populations, all requiring analgesic treatment for moderate-to-severe chronic pain. METHODS Three equally sized age-groups (A>/=65, n=30; B=51 to 64, n=27; C</=50 y, n=25) were examined during 28-day treatment periods to detect potential(More)
OBJECTIVE To assess treatment with the 5% lidocaine medicated plaster for peripheral neuropathic pain after disk herniation. STUDY DESIGN Case series, single center, retrospective data. PATIENTS AND METHODS Data of 23 patients treated for neuropathic pain with the lidocaine plaster for up to 24 months after a protrusion or prolapse of the cervical,(More)
Vorgestellt wird der Fall eines 63-jährigen männlichen Patienten, der bei ausgedehnten postoperativen Wundheilungsstörungen im Bereich der unteren Extremität nach primär frustraner medikamentöser Schmerztherapie durch wiederholte Epiduralkatheter behandelt wurde. Im Verlauf kam es bei fehlenden neurologischen Symptomen als Zufallsbefund zur Diagnosestellung(More)
Wir untersuchten, ob P-STIM (Akupunktur mit Stimulation), bei laparoskopischen Nephrektomien im Hinblick auf akute Schmerzen peri- und postoperativ eingesetzt, einen niedrigeren Analgetikaverbrauch bzw. eine Verbesserung des Schmerzscores gegenüber Placebo bewirkt. Die Studie wurde doppelblind, randomisiert, kontrolliert durchgeführt. 44 Patienten wurden(More)
This case report describes a 63-year-old male patient with considerably impaired postoperative wound healing in the region of the lower extremities. After initial drug therapy for the pain was ineffectual, the patient was treated repeatedly through an epidural catheter. In the further course, an extensive spinal epidural abscess was diagnosed as an(More)
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