Inger Miriam Janssen

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Diese systematische Übersicht untersucht den Nutzen von Ginkgo biloba (Ginkgo) bei Alzheimer Demenz hinsichtlich patientenrelevanter Endpunkte. Dazu wurden elektronische Datenbanken und Studienregister nach randomisiert kontrollierten Studien durchsucht, die einen Vergleich von Ginkgo und Plazebo oder einer anderen Therapieoption untersuchten. Hersteller(More)
UNLABELLED Randomized controlled trials (RCTs) add important information to diagnostic accuracy studies in the evaluation of PET and PET/CT. We evaluated how many RCTs on PET existed, which clinical topics they addressed, and what their design and quality were. METHODS We searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials(More)
BACKGROUND Chronic kidney disease is an increasing health problem worldwide and in its final stage (stage V) can only be treated by renal replacement therapy, mostly hemodialysis. Hemodialysis has a major influence on the everyday life of patients and many patients report dissatisfaction with treatment. Little is known about which aspects of treatment are(More)
BACKGROUND Evidence synthesis has seen major methodological advances in reducing uncertainty and estimating the sizes of the effects. Much less is known about how to assess the relative value of different outcomes. OBJECTIVE To identify studies that assessed preferences for outcomes in health conditions. METHODS SEARCH STRATEGY we searched MEDLINE,(More)
INTRODUCTION The Institute for Quality and Efficiency in Health Care (IQWiG, Germany) has a statutory mandate to provide patients and their family members as well as the wider public with evidence-based health information ( Since 2006 IQWiG has maintained the publicly available website Currently,(More)
BACKGROUND The selection of important outcomes is a crucial decision for clinical research and health technology assessment (HTA), and there is ongoing debate about which stakeholders should be involved. Hemodialysis is a complex treatment for chronic kidney disease (CKD) and affects many outcomes. Apart from obvious outcomes, such as mortality, morbidity(More)
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