Ingeburg Schauer

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Administration of 120 mg propranolol per day to hypertensive patients is followed by decreased plasma concentrations of total cholesterol and HDL cholesterol and increased concentrations of triglycerides. Postheparin lipolytic activity was reduced when measured 5 min after heparin administration. The activity of lecithin:cholesterol acyltransferase is(More)
Within the framework of medical check-ups of heart and circulatory system 1,296 women at the age from 15 to 49 years were examined in two Erfurt large plants. Women with hormonal contraception in the age groups 30-34, 35-39 and 45-49 showed statistically significantly higher mean values of the systolic blood pressure than women without oral contraception.(More)
A micromethod for determination of serum triglyceride concentrations using the Sumal-system and the sampler Sumal PVS 100 will be described. The results show that the qualitative, technical and economic parameters of the method (coefficient of variation 5%, 500 specimens per day and examiner, cost of reagents 0.50 M per test) correspond to the requirements(More)
141 children and adolescents (7-21 years, mean age 14.2 years) showed values of blood pressure, total cholesterol and triglycerides greater than or equal to 90 percentile and HDL-cholesterol values less than or equal to 10 during an examination of 639 children of parents with distinct coronary risk factors or early percentile infarction. By randomization(More)
The changes in some parameters of plasma lipoprotein metabolism in 25 hypertensive men, caused by a two months lasting oral treatment with 120 mg propranolol/day, were compared to the changes that occur during the same time in the subjects (n = 9) of an untreated control group. Propranolol led to an increase of triglycerides and a decrease of HDL(More)
The effects of L-adrenaline and L-noradrenaline on human lecithin: cholesterol acyltransferase (LCAT) activity were investigated in vitro. Both catecholamines are shown to be inhibitors of this enzyme. Despite inter-individual variations in the dose-response relationships calculated for both hormones, significant effects can be expected in the upper(More)
Metabolic side effects of some beta-blockers may outweigh the beneficial influence of lowering blood pressure on coronary heart disease. Propranolol (nonselective; no intrinsic sympathomimetic activity, ISA) and metoprolol (beta-I selective; no ISA), for instance, cause an increase in serum triglycerides and a decrease in high-density lipopl-otein(More)
In vitro effects of DL-propranolol (a therapeutically used beta-blocker with local anesthetic properties), L-propranolol (having both beta-blocking and unspecific local anesthetic properties), D-propranolol (having local anesthetic, but much less beta-blocking properties), and talinolol (a therapeutically used beta-1-blocker with much less local anesthetic(More)
Recently propranolol was found to inhibit human lecithin: cholesterol acyl transferase (LCAT) activity both after oral treatment and after addition to plasma in vitro. Now the dose-response relationship of the propranolol effect on LCAT activity was evaluated in vitro. Concentrations required to produce half-maximal effects in 7 men ranged from 32.4 to(More)