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Using electro-oculography, we quantitatively investigated eye movements in nine heavy cocaine abusers and three groups of controls. Plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG), a major metabolite of brain norepinephrine, in cocaine abusers were reduced to an average of 53% of normal. Cocaine abusers had normal smooth pursuit, optokinetic(More)
AIMS To investigate (1). whether aggressive and delinquent behaviour problems predict subsequent adolescent drinking behaviour; and (2). to what extent this association is mediated by alcohol expectancies and/or peer delinquency/substance use. METHODS 147 adolescents (approximately 15 years old) were interviewed with regard to their drinking behaviour. In(More)
Telescopic spectacles can theoretically improve function of low vision patients by enlarging retinal images. However, unintended head movement may produce sufficient instability of enlarged retinal images to negate the visual benefit. We investigated this phenomenon as a cause of failure in 38 low vision patients who had previously attempted use of(More)
OBJECTIVE While there are numerous studies on the mental sequelae of political imprisonment in the former German Democratic Republic (GDR), there is little knowledge about the prevalence of mental disorders in victims of other forms of political persecution. METHODS 74 individuals, who were subject to non-criminal repressions in the GDR, were investigated(More)
BACKGROUND/AIMS The application of intranasal oxytocin enhances facial emotion recognition in normal subjects and in subjects with autism spectrum disorders (ASD). In addition, various features of social cognition have been associated with variants of the oxytocin receptor gene (OXTR). Therefore, we tested for associations between mind-reading, a measure(More)
In this study, we examined the associations between depression and aspects of emotional functioning, namely emotion recognition, affectivity and interpersonal problems. Particularly, the moderating role of emotion regulation in these interrelations was tested in a sample of 85 women, who exhibited a wide range of depressive symptoms (Composite International(More)
OBJECTIVE The purpose of this longitudinal study was to investigate the relationship between temperament (novelty seeking, harm avoidance and reward dependence), alcohol expectancies, membership in a deviant/substance-using peergroup and drinking behaviour of adolescents drawn from a general population. METHODS 147 adolescents about 15 years of age were(More)
BACKGROUND There are only few data about the prevalence and familiarity of personality disorders (PD) in population based samples in Germany. Moreover, nearly no information exists for the prevalence of PDs among young adults. Thus, in the current study we examined the prevalence, familiarity and psychopathology of PDs, whereby middle-aged adults (about 45(More)
AIM Contradictory results have been produced by previous research on the question to what extent do children of alcoholics (COAs) differ in measures of externalizing symptoms from children of non-alcoholic parents. The goal of this study was to determine whether COAs are characterized by more behavioural problems than non-COAs, and also to determine the(More)
The authors longitudinally investigated the familial transmission of mothers' BPD symptoms to their offspring, taking maternal depression into consideration. The sample consisted of 323 offspring and their mothers from the community-based Greifswald Family Study. These families were examined for the first time when the children were about 15 years old(More)