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The malaria parasite contains a nuclear genome with 14 chromosomes and two extrachromosomal DNA molecules of 6 kb and 35 kb in size. The smallest genome, known as the 6 kb element or mitochondrial DNA, has been sequenced from several Plasmodium falciparum isolates because this is a potential drug target. Here we describe the complete nucleotide sequence of(More)
MicroRNAs (miRNAs) are tiny non-coding regulatory molecules that modulate plant’s gene expression either by cleaving or repressing their mRNA targets. To unravel the plant actions in response to various environmental factors, identification of stress related miRNAs is essential. For understanding the regulatory behaviour of various abiotic stresses and(More)
The present study illustrates the effect of 24-epibrassinolide (24-EBL) on morphological and biochemical parameters in radish (Raphanus sativus L.) seedlings grown under nickel (Ni) ion stress. The radish seeds pre-soaked in different concentrations of 24-EBL were sown in petridishes containing various concentrations of heavy metal (Ni).Observations were(More)
BACKGROUND Stripe rust, leaf rust, tan spot, and Karnal bunt are economically significant diseases impacting wheat production. The objectives of this study were to identify quantitative trait loci for resistance to these diseases in a recombinant inbred line (RIL) from a cross HD29/WH542, and to evaluate the evidence for the presence loci on chromosome(More)
OBJECTIVE To investigate the involvement of 8-iso-PGF(2alpha) and 25-hydroxycholesterol (25-OH-Chol) in the pathophysiology of endometriosis. DESIGN Observational case-control study using enzyme immunoassay and high-performance liquid chromatography (HPLC). SETTING Postgraduate Institute of Medical Education and Research. PATIENT(S) Forty-five women(More)
OBJECTIVE To investigate the involvement of the receptor gene for advanced glycation (RAGE), its ligand EN-RAGE, and COX-2 in endometriosis. METHODS The mRNA and protein expression of the corresponding genes were determined from endometriotic cells from 28 study patients and healthy endometrial stromal cells from 20 controls by semiquantitative RT-PCR and(More)
Malaria transmission is dependent on the development of sexual forms of Plasmodium falciparum, called gametocytes, in the vertebrate host. Pfg27 is an abundantly expressed sexual stage-specific protein that is essential for gametocytogenesis in P. falciparum. We describe the crystal structure of Pfg27, which reveals a novel fold composed of two pseudo(More)
Small heat shock proteins (sHSPs) are chaperones that play an important role in various developmental, biotic and abiotic stresses. The sHSP family possess a conserved domain of approximately 80 to 100 amino acids called alpha-crystalline domain (ACD), flanked by N- and C-terminal regions. Search for complete proteomes and expressed sequenced tag (EST)(More)
28-Homobrassinolide (28-HBL), a brassinosteroid is reported to play significant role in diverse physiological processes. It induces a range of cellular and adaptive responses to a range of environmental stresses. Cadmium (Cd) is a non-essential metal which alters various physiological processes and generates ROS, which can oxidize biological macromolecules(More)