Inder M Verma

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In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.

Luigi Naldini, Ulrike Blömer, +5 authors Didier Trono
Science
1996

A retroviral vector system based on the human immunodeficiency virus (HIV) was developed that, in contrast to a murine leukemia virus-based counterpart, transduced heterologous sequences into HeLa… (More)

NF-kappaB regulation in the immune system.

Qiutang Li, Inder M Verma
Nature reviews. Immunology
2002

The nuclear factor-kappaB (NF-kappaB)/REL family of transcription factors has a central role in coordinating the expression of a wide variety of genes that control immune responses. There has been… (More)

NF-κB regulation in the immune system

Qiutang Li, Inder M Verma
Nature Reviews Immunology
2002

The nuclear factor-κB (NF-κB)/REL family of transcription factors has a central role in coordinating the expression of a wide variety of genes that control immune responses. There has been intense… (More)

Suppression of TNF-alpha-induced apoptosis by NF-kappaB.

D J Van Antwerp, Seamus J. Martin, Tal Kafri, Douglas R Green, Inder M Verma
Science
1996

Tumor necrosis factor alpha (TNF-alpha) signaling gives rise to a number of events, including activation of transcription factor NF-kappaB and programmed cell death (apoptosis). Previous studies of… (More)

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

Luigi Naldini, Ulrike Blömer, Fred H. Gage, Didier Trono, Inder M Verma
Proceedings of the National Academy of Sciences…
1996

We describe the construction of a safe, replication-defective and efficient lentiviral vector suitable for in vivo gene delivery. The reverse transcription of the vector was found to be a… (More)

Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network

Andrew Chi-Yeu Liu, David K. Welsh, +10 authors Steve A Kay
Cell
2007

Molecular mechanisms of the mammalian circadian clock have been studied primarily by genetic perturbation and behavioral analysis. Here, we used bioluminescence imaging to monitor Per2 gene… (More)

Development of a self-inactivating lentivirus vector.

Hiroyuki Miyoshi, Ulrike Blömer, Masayo Takahashi, Fred H. Gage, Inder M Verma
Journal of virology
1998

We have constructed a new series of lentivirus vectors based on human immunodeficiency virus type 1 (HIV-1) that can transduce nondividing cells. The U3 region of the 5' long terminal repeat (LTR) in… (More)

BRCA1 tumor suppression occurs via heterochromatin mediated silencing

Quan Zhu, Gerald M. Pao, +5 authors Inder M Verma
Nature
2011

Mutations in the tumour suppressor gene BRCA1 lead to breast and/or ovarian cancer. Here we show that loss of Brca1 in mice results in transcriptional de-repression of the tandemly repeated satellite… (More)

A fourth IkappaB protein within the NF-kappaB signaling module.

Soumen Basak, Hana Kim, +8 authors Alexander Hoffmann
Cell
2007

Inflammatory NF-kappaB/RelA activation is mediated by the three canonical inhibitors, IkappaBalpha, -beta, and -epsilon. We report here the characterization of a fourth inhibitor, nfkappab2/p100,… (More)

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

Inder M Verma, John K Stevenson, Eric. M. Schwarz, D R Van Antwerp, Shigeki Miyamoto
Genes & development
1995

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