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We report the clinical and genetic characteristics of a five-generation family (MN1) with an unusual form of myotonic dystrophy (DM). Affected individuals have clinical features that are similar to DM including myotonia, distal weakness, frontal balding, polychromatic cataracts, infertility and cardiac arrhythmias. Genetic analyses reveal that affected(More)
In the aftermath of the severe flooding in Central Europe in August 2002, a number of changes in flood policies were launched in Germany and other European countries, aiming at improved risk management. The question arises as to whether these changes have already had an impact on the residents’ ability to cope with floods, and whether flood-affected private(More)
Assessing and mapping damage risk of floods for large river basins is still in its infancy. Damage risk is understood to be the combination of flood hazard and the vulnerability of communities to a flood of a particular return period. Risk is calculated and mapped for two communities in which dykes are not located for flood protection: Meissen on the Elbe(More)
River polders are retention basins contained by levees alongside rivers into which water from the main river channel is diverted during extreme floods in order to cap the peak discharge of the flood hydrograph and to alleviate downstream flood risk by reducing the water levels. The retained water, however, is stagnant and the organic material in the water(More)
Pluvial floods have caused severe damage to urban areas in recent years. With a projected increase in extreme precipitation as well as an ongoing urbanization, pluvial flood damage is expected to increase in the future. Therefore, further insights, especially on the adverse consequences of pluvial floods and their mitigation, are needed. To gain more(More)
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