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The objective of this study was to investigate the reliability and validity of the Pittsburgh Sleep Quality Index (PSQI) in a non-clinical sample consisting of younger and older adults. There has been little research validating the PSQI with respect to multinight recording as with actigraphy, and more validation is needed in samples not specifically(More)
OBJECTIVES To compare relationships between the sleep-wake cycle and endogenous circadian rhythms in young and older adults and to examine correlates between evening naps and circadian rhythms in older adults. DESIGN For 1 week of home recording, subjects wore wrist-activity monitors and kept daily sleep logs. After the home monitoring, subjects entered(More)
This study was undertaken to investigate regional metabolic abnormalities and to determine the effects of modafinil in narcoleptics on cerebral glucose metabolism using [(18)F] fluorodeoxyglucose positron emission tomography (FDG PET). Eight narcoleptic patients participated in the study. Two [(18)F] FDG PET scans were obtained before and after 2 weeks of(More)
The aim of this study was to contrast the time distribution of out-of-bed napping in young and older adults through recordings of wrist activity, and to evaluate the correlates of napping with nocturnal sleep. Seventy-three young adults between 18 and 32 years and 60 older adults between 60 and 75 years of age participated in the study. Subjects were(More)
We evaluated the effect of OROS methylphenidate (MPH) on sleep quality and architecture in children with attention-deficit/hyperactivity disorder (ADHD) using both a parental sleep questionnaire and polysomnography. Twenty-four ADHD children who had no comorbid psychiatric or sleep disorders except for oppositional defiant disorder completed the 6-week,(More)
Evidence from previous studies suggests autonomic dysregulation in patients with major depressive disorder (MDD). Antidepressant treatment may also affect central autonomic function. We investigated whether the type of antidepressant might be associated with the pattern of cardiorespiratory coordination in non-depressed women with recurrent MDD. Resting(More)
Urinary luteinizing hormone (LH) and the melatonin metabolite (6-sulfatoxymelatonin; aMT6s) were measured in normal young men following early morning light exposure. Eleven young healthy men ages 19-30 years participated in this study. During separate weeks in counterbalanced order, each subject received both 5 days of bright light treatment (BL) and 5 days(More)
STUDY OBJECTIVES To assess sleep characteristics in children with ADHD through polysomnographic recordings and parental reports of sleep problems. METHODS Standard overnight polysomnography evaluation was performed to record sleep in 27 children with ADHD and 26 healthy controls, aged 7 to 12 years. The diagnosis of ADHD was determined by the Korean(More)
IMPORTANCE This study presents an innovative method for developing a neuromuscular model of obstructive sleep apnea (OSA). OBJECTIVE To establish a new OSA animal model simulating real upper airway conditions during sleep. DESIGN AND SETTING In vivo animal study at an academic tertiary referral center. SUBJECTS A total of 27 New Zealand white male(More)
OBJECTIVE To determine the predictors affecting treatment outcome after application of the mandibular advancement device (MAD). DESIGN Retrospective analysis. SETTING Tertiary care university hospital. PATIENTS A total of 76 patients (68 men and 8 women) who were treated with the MAD for obstructive sleep apnea (OSA) were included from September 2005(More)