• Publications
  • Influence
Antioxidant and anti-inflammatory activities of zinc oxide nanoparticles synthesized using Polygala tenuifolia root extract.
TLDR
ZnO NPs demonstrated moderate antioxidant activity by scavenging 45.47% DPPH at 1mg/mL and revealed excellent anti-inflammatory activity by dose-dependently suppressing both mRNA and protein expressions of iNOS, COX-2,IL-1β, IL-6 and TNF-α. Expand
In-vitro anticancer activity of green synthesized silver nanoparticles on MCF-7 human breast cancer cells.
TLDR
Silver NPs were found to be significantly toxic to MCF-7 cells via the induction of apoptosis whereas sparing normal immune system cells, and characterized using UV-Vis spectroscopy, FTIR, SEM-ED, TEM and SAED. Expand
Cinnamyl alcohol attenuates vasoconstriction by activation of K+ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase
TLDR
It is suggested that CAL induces vasorelaxation by activating K+ channels via the NO-cGMP-PKG pathway and the inhibition of Rho-kinase. Expand
Inhibitory Effect of Valencene on the Development of Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice
TLDR
Topical application of VAL significantly reduced AD-like symptoms and recovered decreased expression of filaggrin in DNCB-sensitized NC/Nga mice, suggesting that VAL may serve as a potential therapeutic option for AD. Expand
Herbal formula HMC05 prevents human aortic smooth muscle cell migration and proliferation by inhibiting the ERK1/2 MAPK signaling cascade
TLDR
The influence of HMC05 regulation on the MAPK/extracellular signal-regulated kinase (ERK) 1/2 signaling cascade in the inhibition of the migration and proliferation of human aortic smooth muscle cells (HASMCs) is investigated. Expand
Anti-inflammatory and antioxidant effects of coumarins isolated from Foeniculum vulgare in lipopolysaccharide-stimulated macrophages and 12-O-tetradecanoylphorbol-13-acetate-stimulated mice
TLDR
In vivo experiments showed that imperatorin reduced TPA-induced ear thickness/weight, cutaneous cytokines expression and improved histopathological features as well as inhibition of the pro-inflammatory cytokines production in LPS-stimulated mice. Expand
Lotus (Nelumbo nucifera) seedpod extract inhibits cell proliferation and induces apoptosis in non-small cell lung cancer cells via downregulation of Axl.
TLDR
The data suggest that Axl is a novel therapeutic target of LSPE to inhibit cell proliferation and promote apoptosis in NSCLC cells, and further studies to elucidate these compounds might discover a potent therapeutic agent. Expand
Astragali Radix and its compound formononetin ameliorate diesel particulate matter-induced skin barrier disruption by regulation of keratinocyte proliferation and apoptosis.
TLDR
The results suggest that AR and FMT act as anti-pollution agents and alleviate PM induced skin barrier defects through regulation of apoptosis and proliferation in keratinocytes. Expand
Acer palmatum thumb. Ethanol Extract Alleviates Interleukin-6-Induced Barrier Dysfunction and Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation
TLDR
It is suggested that KIOM-2015E protects colitis principally by improving intestinal barrier function and promoting anti-inflammatory responses and thus may be a candidate treatment for IBD. Expand
Vasodilatory effect of kaempferol-7-O-α-L-rhamnopyranoside via NO-cGMP-PKG signaling.
TLDR
Results suggest that KR induces endothelium-dependent vasodilation/vasorelaxation via the NO-cGMP-PKG pathway. Expand
...
1
2
3
4
...