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Plasma disposition of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, in rabbits after oral administration.
The objective of this study was to evaluate the pharmacokinetic profiles of toltrazuril (TZR), and its major metabolites toltrazuril sulfoxide (TZR x SO) and toltrazuril sulfone (TZR x SO(2)) inExpand
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Subacute (28 day) Toxicity of Surfactin C, a Lipopeptide Produced by Bacillus subtilis, in Rats
Surfactin C, produced by acillus subtilis isolated from Korean soybean paste, was given to Sprague-Dawley rats of both sexes at dose of 500, 1000 or 2000 mg/kg for 28 days. There were no surfactinExpand
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Assessment of dermal safety of Scutellaria baicalensis aqueous extract topical application on skin hypersensitivity.
Scutellaria baicalensis has been used as a traditional herbal medicine for bronchitis, hepatitis, and allergic diseases. The root of Scutellaria baicalensis contains active flavonoid components,Expand
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Platycodin D, a triterpenoid sapoinin from Platycodon grandiflorum, ameliorates cisplatin-induced nephrotoxicity in mice.
  • T. Kim, In-Bae Song, +6 authors H. Yun
  • Chemistry, Medicine
  • Food and chemical toxicology : an international…
  • 1 December 2012
Platycodin D (PD) is well known as a potent triterpenoid saponin having various pharmacological activities isolated from the root of Platycodon grandiflorum (Jacq.) A. DC. (Campanulaceae). We aimedExpand
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Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs.
Toltrazuril (TZR) is a triazine-based antiprotozoal agent. Following a single oral administration of TZR at 10 and 20 mg/kg to male pigs, the mean TZR concentration in plasma peaked at 4.24 and 8.18Expand
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Plasma and tissue depletion of florfenicol in olive flounder (Paralichthys olivaceus) after oral administration
Abstract The aim of this study was to evaluate the pharmacokinetics of florfenicol after intravenous (i.v.) and oral (p.o.) administrations and investigate its depletion after multiple oralExpand
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Effect of Surfactin on Growth Performance of Weaning Piglets in Combination with Bacillus subtilis BC1212
The aim of this study is to investigate the effects of surfactin in combination with Bacillus subtilis BC1212 isolated from Korean soybean paste, on feed utilization and growth performance during 4Expand
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Platycodin D attenuates bile duct ligation-induced hepatic injury and fibrosis in mice.
  • T. Kim, H. Lee, +5 authors H. Yun
  • Chemistry, Medicine
  • Food and chemical toxicology : an international…
  • 2013
Platycodin D (PD) is the major triterpene saponin in the root of Platycodon grandiflorum. The aim of the present study was to evaluate the protective effects of PD on bile duct ligation (BDL)-inducedExpand
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Evaluation of Genetic and Developmental Toxicity of Surfactin C from Bacillus subtilis BC1212
Surfactin C is a biosurfactant produced by Bacillus subtilis from Korean soybean paste. Surfactin C is known to have several therapeutic effects including anti-inflammatory, fibrinolytic, andExpand
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Anti-inflammatory effects of talosin A via inhibition of NF-kappaB activation in lipopolysaccharide-stimulated RAW264.7 cells
Aim of work To determine whether talosin A inhibits production of pro-inflammatory cytokines and nitric oxide (NO) in lipopolysaccharide (1 μg/ml)-stimulated RAW 264.7 macrophages. Talosin A (10 andExpand
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