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We present a binding free energy function that consists of force field terms supplemented by solvation terms. We used this function to calibrate the solvation model along with the binding interaction terms in a self-consistent manner. The motivation for this approach was that the solute dielectric-constant dependence of calculated hydration gas-to-water(More)
In this paper, we present a new sliding window based local thresholding technique 'NICK' and give a detailed comparison of some existing sliding-window based thresholding algorithms with our method. The proposed method aims at achieving better binarization results, specifically, for ancient document images. NICK has been inspired from the Niblack's(More)
  • Aneesh P Panoli, Maruthachalam Ravi, Jose Sebastian, Bindu Nishal, Thamalampudi V Reddy, Mohan PA Marimuthu +3 others
  • 2006
BACKGROUND Pairing of homologous chromosomes at meiosis is an important requirement for recombination and balanced chromosome segregation among the products of meiotic division. Recombination is initiated by double strand breaks (DSBs) made by Spo11 followed by interaction of DSB sites with a homologous chromosome. This interaction requires the strand(More)
The establishment of sister chromatid cohesion followed by its controlled release at the metaphase to anaphase transition is necessary for faithful segregation of chromosomes in mitosis and meiosis. Cohesion is established by the action of Ctf7/Eco1 on the cohesin complex during DNA replication following loading of cohesin onto chromatin by the Scc2-Scc4(More)
—Content-based video indexing and retrieval has become an interesting research area with the tremendous growth in the amount of digital media. In addition to the audiovisual content, text appearing in videos can serve as a powerful tool for semantic indexing and retrieval of videos. This paper proposes a method based on edge-features for horizontally(More)
— Codebook-based representations have been effectively employed for writer identification. Most of the codebook-based methods generate a codebook by clustering a set of patterns extracted from an independent data set. The probability of occurrence of the codebook patterns in a given writing is then used to characterize its author. This study investigates(More)