Imran Abdul Khalid

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A hospital based cross-sectional retrospective study was conducted to determine the frequency of hand foot syndrome (HFS) with Capecitabine as a single agent and in combination with Oxaliplatin. The study included 43 consecutive cases of colorectal carcinoma and conducted from June till December 2008. Patients on palliative care were excluded. SPSS was used(More)
OBJECTIVE To determine the association between histological grade of tumour and estrogen progesterone receptors (ER/PR) expression in unselected invasive carcinoma of breast in Malaysian patients. STUDY DESIGN An observational study. PLACE AND DURATION OF STUDY Advanced Medical and Dental Institute and Hospital, Kepala Batas, from year 2002 to 2007. (More)
We determined if therapeutic plasma concentrations of mexiletine (0.75-2.0 microgram/ml) could be maintained in patients admitted to a coronary care unit by twice daily dosing of a new slow-release (S.R.) formulation of mexiletine. Twenty patients, 14 with acute myocardial infarction, entered the first study and received either 250 mg conventional(More)
BACKGROUND To assess the diagnostic potential of tumor-associated high molecular weight DNA in stool samples of 32 colorectal cancer (CRC) patients compared to 32 healthy Malaysian volunteers by means of polymerase chain reaction (PCR). METHODS Stool DNA was isolated and tumor-associated high molecular weight DNA (1.476 kb fragment including exons 6-9 of(More)
Adenomatoid Odontogenic Tumour (AOT) is an unusual benign tumour unique to maxillofacial area, with a tendency to involve the tooth bearing areas of both the jaws and accounting for 3% of all the odontogenic tumours. Diagnosis of the tumour is sometimes intriguing owing to its variable clinical and radiographic presentation. One such variable and relatively(More)
Holter tape analysis is widely used to both confirm and exclude the presence of significant arrhythmias. We have studied the utilisation of the Holter service at Glasgow Royal Infirmary over a period of 6 months. During this period 305 x 24 hour Holter tapes were recorded. Out patient referrals generated 95% of these requests with only 5% of requests for in(More)
Primary sarcomas of the breast are extremely rare comprising less than 1.0% of all malignant tumors of the breast. It is even rarer to be reported in a 25-year-old female. This can cause a diagnostic dilemma not only for the clinician but also for the cytopathologist. A 25-year-old woman presented with a well defined firm, mobile lump in her right breast.(More)
Autophagy is a protein degradation process within the cell and its deregulation has been linked to various diseases and the formation of cancer. Both mTOR and Beclin-1 are important proteins involved in the regulation of autophagy process and tumorigenesis. The aims of the study were to assess the expression of autophagic-related proteins in breast cancer(More)
BACKGROUND Local delivery of antimicrobial agents provides higher concentration of the drug in the periodontal site for longer periods than systemically delivered methods. In the present study an attempt is made to know the efficacy of controlled local drug delivery of doxycycline as an adjunctive treatment in the management of chronic periodontitis. (More)
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