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BACKGROUND Adult invasive pneumococcal disease (IPD) occurs mainly in the elderly and patients with co-morbidities. Little is known about the clinical characteristics, serotypes and genotypes causing IPD in healthy adults. METHODS We studied 745 culture-proven cases of IPD in adult patients aged 18-64 years (1996-2010). Patients were included in two(More)
BACKGROUND Delirium diagnosis in elderly is often complicated by underlying dementia. OBJECTIVE We evaluated performance of the Delirium Rating Scale-Revised-98 (DRS-R98) in patients with high dementia prevalence and also assessed concordance among past and current diagnostic criteria for delirium. METHODS Cross-sectional analysis of newly admitted(More)
BACKGROUND Information on validity and reliability of delirium criteria is necessary for clinicians, researchers, and further developments of DSM or ICD. We compare four DSM and ICD delirium diagnostic criteria versions, which were developed by consensus of experts, with a phenomenology-based natural diagnosis delineated using cluster analysis of delirium(More)
OBJECTIVES The epidemiology of invasive Haemophilus influenzae (Hi) has changed since the introduction of the Hi type b (Hib) vaccine. The aim of this study was to analyze the clinical and molecular epidemiology of Hi invasive disease in adults. METHODS Clinical data of the 82 patients with Hi invasive infections were analyzed. Antimicrobial(More)
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