Imelda Smit

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OBJECTIVE The use of endophenotypes, such as neurological soft signs (NSS), is advocated as one possible method to elucidate the heterogeneity of schizophrenia. Exploring the associations between NSS and specific illness symptoms has revealed some trends, although results have been conflicting. To date, such studies have been conducted largely on Caucasian(More)
The identification of the pharmacokinetic-pharmacodynamic propofol model from noisy measurement data is desirable, since it enables automatic open-and closed-loop drug delivery schemes to adapt to varying patient parameters. In order to investigate the influence of measurement noise on the performance of different nonlinear block-oriented identification(More)
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