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Axonal loss is likely to be an important component of atrophy and the pathological substrate for the fixed disability of MS. To estimate the rate of central white matter reduction we investigated ventricular volume change and disease activity on monthly MRI in 19 patients over 6 months. At baseline, ventricular volumes were largest in primary progressive MS… (More)
Acknowledgements The research summarised in this report was funded by the Department of Health under its Inequalities in Health Research Initiative (project grant 1217443). I am particularly grateful to Hazel Qureshi for supervising the project and to members of the project advisory group for advice and guidance on the research, and for reading draft… (More)
A new guide for carers is being launched this week.