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  • Cornelius J. Mcginn, Mark M. Zalupski, +8 authors Theodore S Lawrence
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2001 (First Publication: 15 November 2001)
  • PURPOSE The primary objective of this phase I trial was to determine the maximum-tolerated dose of radiation that could be delivered to the primary tumor concurrent with full-dose gemcitabine inContinue Reading
  • Imad Shureiqi, Wei Jiang, +7 authors Scott Michael Lippman
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2003 (First Publication: 8 August 2003)
  • Diminished apoptosis, a critical event in tumorigenesis, is linked to down-regulated 15-lipoxygenase-1 (15-LOX-1) expression in colorectal cancer cells. 13-S-hydroxyoctadecadienoic acid (13-S-HODE),Continue Reading
  • Imad Shureiqi, Dongning Chen, +6 authors Scott Michael Lippman
  • Biology, Medicine
  • Journal of the National Cancer Institute
  • 2000 (First Publication: 19 July 2000)
  • BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) appear to act via induction of apoptosis-programmed cell death-as potential colorectal cancer chemopreventive agents. NSAIDs can alter theContinue Reading
  • David S. Hong, Van K Morris, +18 authors Scott Kopetz
  • Medicine, Biology
  • Cancer discovery
  • 2016 (First Publication: 1 December 2016)
  • In vitro, EGFR inhibition, combined with the BRAF inhibitor vemurafenib, causes synergistic cytotoxicity for BRAFV600E metastatic colorectal cancer, further augmented by irinotecan. The safety andContinue Reading