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Fluorescence in situ hybridization (FISH) analysis has shown previously that 10-15% of chronic myeloid leukemias (CML) have hemizygous deletions of variable sizes affecting regions that flank the ABL and BCR translocation breakpoints on the derivative chromosome 9, and these patients have a poor outcome. FISH studies using large commercial genomic probes(More)
The Wireless Internet Collaboration System allows wireless smartphones to be used for mathematics communication, that is, for the creation and exchange of mathematical formulas, diagrams, and text between two or more participants. The system solves the problem of providing the expressive power of mathematical notation on devices with limited input, output,(More)
This paper presents a volumetric approach to reconstructing a smooth surface from a sparse set of parallel binary contours, e.g. those produced via histologic imaging. It creates a volume dataset by interpolating 2D filtered distance fields. The zero isosurface embedded in the computed volume provides the desired result. MPU implicit functions are fit to(More)
This paper presents a technique for creating a smooth, closed surface from a set of 2D contours, which have been extracted from a 3D scan. The technique interprets the pixels that make up the contours as points in ℝ(3) and employs Multi-level Partition of Unity (MPU) implicit models to create a surface that approximately fits to the 3D points. Since MPU(More)
Environment for Authoring Design Semantics Design is a ubiquitous human activity and a critical aspect of many modern industries. CAD tools have revolutionized product development in the automotive and aerospace (mechanical CAD) and architecture, engineering, and construction (AEC) industries, as well as other areas where geometric computation and(More)
In this paper we present MUG, a collaborative 3D environment to support knowledge-based conceptual design. This work integrates Computer-Aided and Collaborative Design methods with representation framework being developed for the Semantic Web. In this work, we have created a unique environment that allows a group of users, working together over the(More)
Information security and assurance are new frontiers for collaborative design. In this context, information assurance (IA) refers to methodologies to protect engineering information by ensuring its availability, confidentiality, integrity, non-repudiation, authentication, access control, etc. In collaborative design, IA techniques are needed to protect(More)
This paper provides a framework for information assurance within collaborative design based on a technique we call rolebased viewing. Role-based viewing enables role-based access control through geometric partitioning of 3D models. The partitioning is used to create variable level-of-detail (LOD) meshes, across both individual parts and assemblies, to(More)
Information security and assurance are new frontiers for collaborative design. In this context, information assurance (IA) refers to methodologies to protect engineering information by ensuring its availability, confidentiality, integrity, non-repudiation, authentication, access control, etc. In collaborative design, IA techniques are needed to protect(More)