Ilja Kubisch

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OBJECTIVE The aim of this study was to develop an immunomagnetic/real-time reverse transcriptase polymerase chain reaction (RT-PCR) assay and assess its clinical value for the molecular detection of circulating tumor cells (CTCs) in peripheral blood of pancreatic cancer patients. METHODS The presence of CTCs was evaluated in 34 pancreatic cancer patients(More)
The aim of this study was to assess the prognostic and predictive values of circulating tumor cell (CTC) analysis in colorectal cancer patients. Presence of CTCs was evaluated in 60 colorectal cancer patients before systemic therapy - from which 33 patients were also evaluable for CTC analysis during the first 3 months of treatment - through immunomagnetic(More)
We report a unique case of a 71-year-old female patient with epidermolysis bullosa acquisita. The patient initially presented with the clinical symptoms of bilateral eyelid dermatitis that occurred several months prior to the development of oral and pharyngeal erosions and blisters. While no contact allergy was found by patch testing, direct(More)
e14042 Background: The role of circulating tumor cells (CTCs) in peripheral blood of cancer patients as an indicator of tumor recurrence has not been clearly established. This study aims to evaluate the use a multimarker panel for detection and characterization of CTCs in colorectal cancer patients and its utility in predicting clinical outcome. METHODS(More)
e14657 Background: Pancreatic cancer is an aggressive malignancy with mortality levels almost equal to its incidence. Despite remarkable advances having been achieved, the treatment results are still disappointing and there is an urgent need for better prognostic tools. This study aims to develop an accurate immunomagnetic assay followed by the validation(More)
e14655 Background: Despite progress in the treatment of advanced gastric cancer, therapy resistance and high mortality continue to pose major problems in clinical management. This study aims to develop an accurate immunomagnetic assay followed by the validation of a multimarker panel for detection of circulating tumor cells (CTCs) in peripheral blood of(More)
BACKGROUND The analysis of circulating tumor cells (CTCs) is emerging as a promising diagnostic tool in oncology. However, even if a variety of methods for CTC isolation have been already developed, their specificity and/or sensitivity still remain problematic. The aim of this study was to develop an immunomagnetic/real-time reverse transcription polymerase(More)
OBJECTIVE We aimed to assess the prognostic value of circulating tumor cells (CTC) in patients with advanced gastric and gastroesophageal adenocarcinomas. METHODS The presence of CTC was evaluated in 62 patients with advanced gastric and gastroesophageal adenocarcinomas before systemic therapy and at follow-up through immunomagnetic enrichment for mucin(More)
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