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biotechnology, chemical and bioprocesses reduction and control of organic waste / by-products; pollution prevention through tuning complex chemical processes and bioprocesses treatment of waste and wastewater, scale-up and application of bioremediation processes, reduction or control of organic air emissions. Dynamic soil-structure interaction, piles under… (More)
Arterial walls typically have a heterogeneous structure with three different layers (intima, media, and adventitia). Each layer can be modeled as a fiber-reinforced material with two families of relatively stiff collagenous fibers symmetrically arranged within an isotropic soft ground matrix. In this paper, we present two different modeling approaches, the… (More)
My research interests lie in the areas of computational solid mechanics and nonlinear dynamics with recent emphasis on method development for simulations of systems with dynamic instabilities and on the modelling and optimization of patterned and layered hydrogel systems for biomedical applications.
Layered constructs from poly(ethylene glycol) (PEG) hydrogels and chicken eggshell membranes (ESMs) are fabricated, which can be further cross-linked by glutaraldehyde (GA) to form GA-PEG-ESM composites. Our results indicate that ESMs composed of protein fibrous networks show elastic moduli ∼3.3-5.0 MPa and elongation percentages ∼47-56%, close to human… (More)
This paper presents a computational framework to simulate the mechanical behavior of fibrous biomaterials with randomly distributed fiber networks. A random walk algorithm is implemented to generate the synthetic fiber network in 2D used in simulations. The embedded fiber approach is then adopted to model the fibers as embedded truss elements in the ground… (More)
Poly(ethylene glycol) diacrylate (PEGDA) hydrogels can be potentially used as scaffold material for tissue engineered heart valves (TEHVs) due to their good biocompatibility and biomechanical tunability. The photolithographic patterning technique is an effective approach to pattern PEGDA hydrogels to mimic the mechanical behavior of native biological… (More)