Ilaria Bosio

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Neutropenia encompasses a family of neutropenic disorders, both permanent and intermittent, ranging from severe (<500 neutrophils/mm(3)) to mild (500-1500 neutrophils/mm(3)), which may also affect other organ systems such as the pancreas, central nervous system, heart, muscle and skin. Neutropenia can lead to life-threatening pyogenic infections whose(More)
Introduction Arterial or venous thrombosis rarely occurs in children, in almost 70% of these patients an acquired or congenital cause can be identified. Hereditary thrombophilia can be identified in 10-30% of children with other evident causes of thrombosis, and in 60% of children with apparent idiopathic thrombosis. Therefore it is suggested that(More)
Results In our cohort (148 males and 120 females) fever began at 26.2 + 24 months of age. 8% of the patients had an onset after the fifth year of life, but all other Thomas criteria were met. A family history was present in 39.6% of patients. Mean duration of PFAPA episodes was 4 + 1.6 days, and a mean interval between episodes 27.9 + 11 days. Most common(More)
Introduction PFAPA syndrome is the most common cause of periodic fevers in children. In the clinical setting of children with periodic fever, there are a minority of patients in which to differentiate between PFAPA and monogenic periodic fevers is not immediate. The Gaslini score would provide a useful tool in this setting, calculating the probability to(More)
Results In our cohort (148 males and 120 females) fever began at 26.2 ± 24 months of age. 8% of the patients had an onset after the fifth year of life, but all other Thomas criteria were met. A family history was present in 39.6% of patients. Mean duration of PFAPA episodes was 4 ± 1.6 days, and a mean interval between episodes 27.9 ± 11 days. Most common(More)
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