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OBJECTIVE To evaluate the benefit of niacin in addition to statin therapy on plaque regression among older individuals with established atherosclerosis. DESIGN Randomised, controlled, double-blind clinical trial. SETTING University outpatient center. PATIENTS 145 patients older than 65 years, half of them older than 75 years of age, with established(More)
INTRODUCTION Coronary computed tomography angiography (CCTA) allows for non-invasive coronary artery disease (CAD) phenotyping. There are still some uncertainties regarding the impact this knowledge has on the clinical care of patients. OBJECTIVE To determine whether CAD phenotyping by CCTA influences clinical decision making by the prescription of(More)
Number of subjects currently participating in high-endurance aerobic exercise training regimens and competitions has substantially increased in recent years. While there is no doubt that regular exercise practice is fundamental for the maintenance of a good health, there have been reports of cardiac structural changes of subjects exposed to strenuous(More)