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Optical based methods for non-invasive measurement of regional blood flow tend to incorrectly assess cerebral blood flow, due to contribution of extra-cerebral tissues to the obtained signal. We demonstrate that spectral analysis of phase-coded light signals, tagged by specific ultrasound patterns, enables differentiation of flow patterns at different(More)
Cerebral autoregulation is a mechanism which maintains constant cerebral blood flow (CBF) despite changes in mean arterial pressure (MAP). Assessing whether this mechanism is intact or impaired and determining its boundaries is important in many clinical settings, where primary or secondary injuries to the brain may occur. Herein we describe the development(More)
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