Ikuo Nakamichi

Learn More
OBJECTIVES To evaluate the association between body mass index (BMI) and all-cause mortality and cardiovascular disease (CVD) in an 80-year-old population. DESIGN Cohort study. SETTING Community-based. PARTICIPANTS Six hundred ninety-seven of 1,282 (54.4%) 80-year-old candidate individuals. MEASUREMENTS The dates and causes of all deaths were(More)
OBJECTIVE Recombinant human granulocyte colony-stimulating factor (rhG-CSF) is a potentially effective therapy for Crohn's disease. The purpose of this study was to test the rhG-CSF in murine dextran sulfate sodium-induced colitis (DSS colitis). MATERIAL AND METHODS Murine colitis was induced by feeding with water containing 3% DSS for 9 days. Six to(More)
BACKGROUND AND AIM microRNAs (miRNAs) have been suggested to be candidates for biomarkers in various diseases including Crohn's disease (CD). To identify possible biomarkers predictive of the therapeutic effect of infliximab in CD, we investigated serum miRNA levels during the induction therapy by the medication. METHODS Nineteen CD patients who were(More)
BACKGROUND Little is known about the association between physical fitness and cognitive function in very elderly people (over 80 years of age). OBJECTIVES To evaluate that relationship in 85-year-old community-dwelling individuals. METHODS Out of 207 participants (90 males, 117 females) who were 85 years old and community-dwelling, 205 completed the(More)
Since little is known about the very elderly population aged 80 years and older, we evaluated the association of quality of life (QoL) in an 85-year-old population with physical fitness measurements assessed at age 80 and 85 years. Two hundred seven individuals (90 males, 117 females) aged 85 years underwent the Short Form-36 (SF-36) questionnaires for QoL(More)
BACKGROUND Immunoglobulin levels are elevated in the older people. However, it is unknown whether these levels are related to mortality. OBJECT To evaluate the association between immunoglobulin levels and mortality. METHODS The study population included 697 individuals (277 males and 420 females) of 1,282 eighty-year-old individuals residing in the(More)
OBJECTIVES Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a relatively rare but serious side effect of bisphosphonate (BP)-based treatments. This retrospective study aimed to investigate the risk factors and predictive markers in cases where patients were refractory to a recommended conservative treatment offered in our hospital. PATIENTS AND(More)
Although many investigations examined the relationship between body mass index (BMI) and mortality, little is known about the possible associations between BMI and disease-specific mortality in very elderly people. Here we evaluated this association in an 80-year-old population. In 1998, 675 residents in Japan's Fukuoka Prefecture participated. They were(More)
BACKGROUND AND AIMS Although serum albumin levels are associated with mortality in non-institutionalized elderly people under 80 years old, as well as in the institutionalized very elderly, little is known about the relationship in community-dwelling very elderly people. We, therefore, examined the association in a Japanese population of 80-year-old(More)
Castleman's disease (CD) appears at ubiquitous lymph nodes. To date, detection of the lesion focus for CD has mainly been carried out by physical examination and radiological findings, such as X-ray analysis, CT and MRI. 18F-FDG PET visualizes the active focus of glucose metabolism and the clinical value has been investigated for many different tumours.(More)