Ikuko Takeyama

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Four cases with acute sensorineural hearing loss on one side and one case with bilateral ear fullness associated with Mycoplasma pneumoniae (MP) were described. These cases were characterized by highly elevated MP complement fixation titer, and cold hemagglutinin titer. All patients experienced cochlear symptoms in an early stage following common cold. In(More)
The epidemiologic evidence that dietary fiber protects against colorectal cancer is equivocal. No large-scale clinical study of the administration of Lactobacillus casei has been reported. We examined whether dietary fiber and L. casei prevented the occurrence of colorectal tumors. Subjects were 398 men and women presently free from tumor who had had at(More)
There are several reports of clinical trials of aspirin in sporadic colon cancer. However, only one double-blind trial of aspirin in patients with familial adenomatous polyposis (FAP) has been reported to date. This double-blind, randomized, placebo-controlled clinical trial was therefore performed to evaluate the influence of low-dose aspirin(More)
In this study, 20 subjects (5 women and 15 men, 22-28 years old) were tested for vertical optokinetic nystagmus (OKN) to establish the asymmetry between up and down OKN responses in humans. The subjects were exposed to both upward and downward OKN stimulus at constant velocities of 30, 40, 50, 60, 70, 80, 90 degrees/s in the upright position. Eye movements(More)
The role of the neuronal activity of nucleus prepositus hypoglossi (NPH) in optokinetic stimulation (OKS) and the changes of the activity between OKS and off-OKS (resting condition) were investigated in 5 adult cats. In order to make OKS velocity equal to retinal slip velocity, the cats' eyes were immobilized. The directions of the OKS were clockwise (CW)(More)
In order to analyze the correlation between immunohistochemical positivity for c-erbB-2 oncoprotein and prognosis in patients with malignant salivary gland tumors, 59 cases of malignant tumors of the major salivary glands, including 35 parotid gland, 20 submaxillary gland and 4 sublingual gland tumors, were studied immunohistochemically using a polyclonal(More)
The nucleus of the optic tract (NOT) in the pretectum is the visuo-motor relay between the retina and preoculomotor structure in the pathway conveying signals responsible for optokinetic nystagmus (OKN) in both afoveate and foveate animals. Unilateral lesions of the NOT abolish OKN toward the side ipsilateral to the lesion. However, what parts of the retina(More)
We studied the effects of simultaneous combination therapy with UFT and radiation for 69 head and neck cases with the same protocol in 6 universities in Kanagawa. Completed cases (cases in which therapeutic effects could be evaluated) totaled 67 patients who could receive more than 40 Gy as a given radiation dose and more than 8.4 g as a total UFT dose.(More)
The inhibitory effect of n-3 polyunsaturated fatty acids on human colorectal cancer has been speculated on from epidemiological data and animal studies. We conducted a long-term trial of docosahexanoic acid (DHA)-concentrated fish oil capsules for patients in a high-risk group for colorectal cancer. During this trial, we experienced three patients with(More)
Melanocytes in human vestibular dark cell areas were observed to have round or spindle-shaped cell bodies with several processes. They were located below the basement membrane but the melanocyte processes were found in the dark cell epithelial layer closely adjacent to the dark cell processes or bodies without any separation from the basement membrane.(More)