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Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability
Abstract Pharmaceutical particle technology is employed to improve poor aqueous solubility of drug compounds that limits in vivo bioavailability owing to their low dissolution rate in theExpand
Complete nucleotide sequence and organization of the mitogenome of the red-spotted apollo butterfly, Parnassius bremeri (Lepidoptera: Papilionidae) and comparison with other lepidopteran insects
It is proposed that the CGA (arginine) sequence functions as the start codon for the COI gene in lepidopteran insects, on the basis of complete mitogenome sequences of lepid insect species, including P. bremeri. Expand
Complete nucleotide sequence and organization of the mitogenome of endangered Eumenis autonoe (Lepidoptera: Nymphalidae)
Phylogenetic reconstruction using the concatenated 13 amino acid and nucleotide sequences of the protein-coding genes (PCGs) consistently supported a close relationship between Bombycoidea and Geometroidea among six available lepidopteran superfamilies and excluding Nymphalidae was consistently concluded to exist. Expand
Characterization of a silkworm thioredoxin peroxidase that is induced by external temperature stimulus and viral infection.
Interestingly, the expression levels of BmTPx enzyme in the fat body were particularly high when B. mori larva was exposed at low and high temperatures or baculovirus infection, suggesting that the Bm TPx seems to play a protective role against oxidative stress caused by temperature stimuli and viral infection. Expand
The complete nucleotide sequence and gene organization of the mitochondrial genome of the oriental mole cricket, Gryllotalpa orientalis (Orthoptera: Gryllotalpidae).
Phylogenetic analysis of nucleotide sequence information from all mt genes supported a monophyletic Diptera, a monopterletic Lepidoptera, a Monophyletics Coleoptera and a monophysletic Endopterygota, suggesting that the complete insect mitogenome sequence has a resolving power to the diversification events within Endoperygota. Expand
The mitochondrial genome of the firefly, Pyrocoelia rufa: complete DNA sequence, genome organization, and phylogenetic analysis with other insects.
Phylogenetic analysis among insect orders confirmed a monophyletic Endopterygota, a monphyletic Mecopterida, a Monophyletics Diptera, amonophyletsic Lepidoptera, and a monophysletic ColeopterA, suggesting that the complete insect mt genome sequence has a resolving power in the diversification events within Endoperygota. Expand
Determination of 1-deoxynojirimycin in Morus alba L. leaves by derivatization with 9-fluorenylmethyl chloroformate followed by reversed-phase high-performance liquid chromatography.
A rapid and reliable method suitable for assays of a large number of Morus alba leaves for 1-deoxynojirimycin (DNJ) has been developed and recovered > 99% of extractable DNJ from the leaves. Expand
The complete nucleotide sequence and gene organization of the mitochondrial genome of the bumblebee, Bombus ignitus (Hymenoptera: Apidae).
The complete 16,434-bp nucleotide sequence of the mitogenome of the bumble bee, Bombus ignitus (Hymenoptera: Apidae), was determined and showed the closest relationship between M. bicolor and B. ignitus. Expand
Complete mitochondrial genomes of five skippers (Lepidoptera: Hesperiidae) and phylogenetic reconstruction of Lepidoptera.
Within Rhopalocera (butterflies and skippers) the familial relationships (Papilionidae+(Hesperiidae+(Pieridae+((Lycaenidae+Riodinidae)+Nymphalidae)))) were strongly supported in all analyses, rendering invalid the superfamily status for Hesperioidea. Expand
cDNA cloning, expression, and enzymatic activity of a cellulase from the mulberry longicorn beetle, Apriona germari.
  • S. Lee, S. R. Kim, +7 authors B. Jin
  • Biology, Medicine
  • Comparative biochemistry and physiology. Part B…
  • 1 September 2004
The Ag-EGase enzyme assay exhibited high activity only in midgut tissue, suggesting that the midGut is the prime site where large quantities of EGase are synthesized for degrading the absorbed cellulose from the diet. Expand