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- M. Magdy, N. Abdel Karim, Ihab Eldessouki, O. Gaber, M. Rahouma, M. Ghareeb
- Medicine, BiologyOncology Research and Treatment
- 6 March 2019
Most of the literature about MS are case reports and small retrospective studies, thus there is limited clinical knowledge of the cases and their presentation and management plans.
Pulmonary sarcomatoid carcinoma: University of Cincinnati experience
Systemic chemotherapy alone did not improve survival in patients with PSC and surgery provides the greatest overall survival benefit and adjuvant chemotherapy may also improve survival.
Lung cancer patients have the highest malignancy-associated suicide rate in USA: a population-based analysis
The cancer-associated suicide rate is nearly twice that of the general population of the United States of America, and the suicide risk is highest among the patients with lung cancer, particularly elderly, widowed, male patients and patients with unfavourable tumour characteristics.
Nivolumab and Ipilimumab in the Treatment of Metastatic Uveal Melanoma: A Single-Center Experience
- V. Karivedu, Ihab Eldessouki, Ahmad Taftaf, Zheng Zhu, Abouelmagd Makramalla, N. Karim
- MedicineCase reports in oncological medicine
- 17 April 2019
The clinical outcome and toxicity associated with the combination of ipilimumab and nivolumab combination support the consideration of immunotherapy in MUM.
Exosomes as a Surrogate Marker for Autophagy in Peripheral Blood, Correlative Data from Phase I Study of Chloroquine in Combination with Carboplatin/Gemcitabine in Advanced Solid Tumors
- N. Abdel-Karim, O. Gaber, Ihab Eldessouki, E. Bahassi, J. Morris
- Medicine, BiologyAsian Pacific journal of cancer prevention…
- 1 December 2019
D detection of autophagy protein LC3-B in exosomes serves as a dynamic method to monitor autophileagy and can be utilized to study the effects of anti-neoplastic agents on autophophagy and mechanisms of drug resistance.
Cardiotoxicity with immune system targeting drugs: a meta-analysis of anti-PD/PD-L1 immunotherapy randomized clinical trials.
There was no reported statistically significant cardiotoxicity associated with anti-PD/PD-L1 use and lung cancer subgroups showed better response and survival rates in IMM.
Cardiac tumors prevalence and mortality: A systematic review and meta-analysis.
Pneumonitis as a complication of immune system targeting drugs?-a meta-analysis of anti-PD/PD-L1 immunotherapy randomized clinical trials.
The results can be used to guide therapy selection and set expectations for treatment effect in patients with high-grade and all-grade pneumonitis when compared to traditional CTH regimens for NSCLC and melanoma.
Small or Non-Small Cell Lung Cancer Based Therapy for Treatment of Large Cell Neuroendocrine Cancer of The Lung? University of Cincinnati Experience
- Ihab Eldessouki, O. Gaber, T. Namad, Jiang Wang, J. Morris, N. Abdel Karim
- MedicineJournal of oncology
- 1 November 2018
Results reveal that outcomes for SCLC or NSCLC treatment strategies in LCNEC patients did not result in survival advantages and future research should be addressing it as a separate entity.
GNQ-209P Mutation in Metastatic Uveal Melanoma and Treatment Outcome
- N. Abdel Karim, Ihab Eldessouki, Z. Corrêa
- Medicine, BiologyCase reports in oncological medicine
- 4 April 2018
A series of patients with metastatic UM with distinct mutational profiles receiving nab-paclitaxel (Abraxane) as a treatment drug are reported, and their responses to treatment and their molecular-profiling results are recorded.