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Excitatory amino-acid carrier 1 (EAAC1) is a high-affinity Na+-dependent L-glutamate/D,L-aspartate cell-membrane transport protein. It is expressed in brain as well as several non-nervous tissues. In brain, EAAC1 is the primary neuronal glutamate transporter. It has a polarized distribution in cells and mainly functions perisynaptically to transport(More)
In addition to their role in the specification of the epidermal pattern in each segment, several segment polarity genes, including gooseberry (gsb), specify cell fate in the Drosophila central nervous system (CNS). Analyses of the gsb CNS phenotype have been complicated by the fact that the previously available gsb mutants, all caused by cytologically(More)
In anaesthetized albino rabbits, the cerebellar flocculus was systematically mapped with a glass microelectrode to identify the location of Purkinje cells that inhibit specific vestibulo-ocular reflex pathways. The effects of microstimulation of the flocculus Purkinje cell layer on vestibular nerve-evoked reflexes to ipsilateral medial rectus, ipsilateral(More)
Super-resolution microscopy (PALM, STORM etc.) provides a plethora of fluorescent signals in dense cellular environments which can be difficult to interpret. Here we describe ClusterViSu, a method for image reconstruction, visualization and quantification of labelled protein clusters, based on Voronoi tessellation of the individual fluorescence events. The(More)
Labeling nuclear proteins with electron dense probes in living cells has been a major challenge due to their inability to penetrate into nuclei. We developed a lipid-based approach for delivering antibodies coupled to 0.8 nm ultrasmall gold particles into the nucleus to label RNA polymerase II. Focussed Ion Beam slicing coupled to Scanning Electron(More)
After the inferior olive of the rats had been destroyed by administration of 3-Acetylpyridine, the inhibitory effect of cerebellar stimulation on Deiters neurons was substantially reduced, indicating impairment in functions of Purkinje cells and/or their axons after deprivation of climbing fiber afferents from the cerebellum.
According to psychological research erotic images are evaluated in the context of positive emotions as the most intense, most associated with emotional arousal, among the variety of pleasant and unpleasant stimuli. However it is difficult to separate areas of the brain that are related to the general emotional process from the activity of the brain areas(More)
Exclusive production of the isoscalar vector mesons ω and φ is measured with a 190 GeV/c proton beam impinging on a liquid hydrogen target. Cross section ratios are determined in three intervals of the Feynman variable x F of the fast proton. A significant violation of the OZI rule is found, confirming earlier findings. Its kinematic dependence on x F and(More)
15 a r t i c l e i n f o a b s t r a c t 0 mesons was studied at the COMPASS experiment by scattering 160 GeV/c muons off transversely polarised protons. Five single-spin and three double-spin azimuthal asymmetries were measured as a function of Q 2 , x B j , or p 2 T. The sinφ S asymmetry is found to be −0.019 ± 0.008(stat.) ± 0.003(syst.). All other(More)