Igor Marchetti

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A neurobiological account of cognitive vulnerability for recurrent depression is presented based on recent developments of resting state neural networks. We propose that alterations in the interplay between task positive (TP) and task negative (TN) elements of the Default Mode Network (DMN) act as a neurobiological risk factor for recurrent depression(More)
OBJECTIVES Intensified repetitive transcranial magnetic stimulation (rTMS) applied to the left dorsolateral prefrontal cortex (DLPFC) may result in fast clinical responses in treatment resistant depression (TRD). In these kinds of patients, subgenual anterior cingulate cortex (sgACC) functional connectivity (FC) seems to be consistently disturbed. So far,(More)
The cognitive model of OCD proposes that certain beliefs may contribute to the development and maintenance of this disorder. To date, however, it is not yet clear which beliefs are more relevant for explaining OCD symptomatology; moreover, their causal status is yet to be clearly established. In the effort to identify other constructs and processes related(More)
Copyediting, typesetting, and review of the resulting proofs will be undertaken on this manuscript before final publication. During production and pre-press, errors may be discovered that could affect the content. Abstract Resting state provides an important condition to study depressogenic cognition as neuropsychological studies have associated rest with(More)
Mindwandering (MW) is associated with both positive and negative outcomes. Among the latter, negative mood and negative cognitions have been reported. However, the underlying mechanisms linking mindwandering to negative mood and cognition are still unclear. We hypothesized that MW could either directly enhance negative thinking or indirectly heighten the(More)
Human minds often engage in thoughts and feelings that are self-generated rather than stimulus-dependent, such as daydreaming. Recent research suggests that under certain circumstances, daydreaming is associated with adverse effects on cognition and affect. Based on recent literature about the influence of resting mind in relation to rumination and(More)
INTRODUCTION Human beings live in a social context, where interacting with others is crucial for survival, and having a clear representation of both the “self” and the “other” is needed (Baumeister, 2011). Interestingly, neuroscience has traditionally adopted a Cartesian perspective by which the self is a solipsistic and self-sufficient unit, fundamentally(More)
There is increasing interest in spontaneous thought, namely task-unrelated or rest-related mental activity. Spontaneous thought is an umbrella term for processes like mindwandering, involuntary autobiographical memory, and daydreaming, with evidence elucidating adaptive and maladaptive consequences. In this theoretical framework, we propose that, apart from(More)
BACKGROUND Attentional and memory biases are viewed as crucial cognitive processes underlying symptoms of depression. However, it is still unclear whether these two biases are uniquely related to depression or whether they show substantial overlap. METHODS We investigated the degree of specificity and overlap of attentional and memory biases for(More)