Ignacio Zarante

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OBJECTIVE To estimate the prevalence of congenital heart defects in Colombia using the methodology of the Latin-American Collaborative Study of Congenital Malformations (ECLAMC, for its initials in Spanish) and to make an epidemiological description of the study population. MATERIAL AND METHODS A prospective case-control study nested to a hospital-based(More)
Laboratorio de Parasitología Molecular, Departamento de Microbiología, Facultad de Ciencias, Universidad Javeriana, Carrera 7 No. 43-82, Ed. Felix Restrepo, Of.111, Santafé de Bogotá, Colombia *Laboratorio de Parasitología, Instituto Nacional de Salud, Av. El Dorado con Carrera 50, Santafé de Bogotá, Colombia **Instituto de Genética, Facultad de Medicina,(More)
INTRODUCTION AND OBJECTIVES Microtia is a major malformation of the auricle, comprising a clinical spectrum ranging from a slight reduction in the size of the auricle or one of its parts to the complete absence of the pinna (anotia). Its prevalence varies according to the region of the world it is evaluated in. We analyzed a range of maternal, neonatal, and(More)
BACKGROUND One hospital in the city of Cali, Colombia, of the ECLAMC (Latin-American Collaborative Study of Congenital Malformations) network, reported the unusual occurrence of four cases of sirenomelia within a 55-day period. METHODS An ECLAMC routine for cluster evaluation (RUMOR) was followed that included: calculations of observed/expected ratios,(More)
Congenital anomalies contribute greatly to child mortality and physical disabilities. Strategies used around the world to reduce the frequency and impact of congenital anomalies require epidemiologic surveillance systems to verify their effectiveness. In Bogotá, Colombia, implementation of an accurate monitoring system has been challenging. METHODS The(More)
OBJECTIVE To determine the incidence of congenital anomalies of the urinary tract in Colombia and study their association with maternal risk factors. METHODS We performed a register based, case control study using the data from the ECLAMC (Colaborative latinoamerican Study for Congenital Malformations) in Colombia, between June, 2001 and December, 2004.(More)
INTRODUCTION The Instituto de Genética Humana of the Pontificia Universidad Javeriana conducted an epidemiological surveillance of congenital malformations as defined by criteria provided by the Latin American Collaborative Study of Congenital Malformations. OBJECTIVE The frequency of the main congenital malformations were tabulated for major urban(More)
Esophageal achalasia is a well-known pathology with an autosomal recessive pattern of inherence described in the familiar cases. Its principal symptom is dysphagia, secondary to the poor relaxation of the lower esophageal sphincter. Chagas disease is one of the many causes involved in the development of this disease, being of great importance in our country(More)
OBJECTIVE To determine the association between prenatal multivitamin supplementation and congenital genitourinary tract anomalies in a group of Colombian newborn babies included in the Latin-American surveillance program (ECLAMC). STUDY DESIGN We included all neonates born between January 2004 and August 2007 registered in the ECLAMC database. Maternal(More)
INTRODUCTION Congenital anomalies affect 2 to 3% of live births in Colombia and they are currently the leading cause of death in children under 1 year of age in Bogotá, and the third cause of death in children under 1 year of age in Cali. Congenital anomalies are a major factor contributing to fetal and infant mortality and morbidity in the world. Some(More)