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Stochastic resonance (SR) is a phenomenon in which the response of a non-linear system to a weak input signal is optimized by the presence of noise. The aim of this study was to demonstrate the experimental occurrence of SR in electroencephalographic (EEG) activity elicited by mechanical tactile stimuli. Our experiments show that EEG responses evoked by(More)
Internal stochastic resonance is a phenomenon in which the coherence of a non-linear system is enhanced by the presence of a particular, non-zero level of noise generated by internal or external sources without a periodic input signal. The aim of this study was to demonstrate the experimental occurrence of internal stochastic resonance in the coherence(More)
BACKGROUND Glatiramer acetate (GA) and interferon beta-1 are licensed for treating patients with multiple sclerosis (MS). However, they have slightly different indications, side effect profiles, and tolerability. OBJECTIVE The purpose of this study was to assess the benefit-risk (BR) profile of GA in relapse-remitting MS (RRMS) and clinical isolated(More)
Simultaneous recordings of cortical evoked potentials in the posterior sigmoid gyrus, and spontaneous negative cord dorsum potentials (CDPs) of the L6 lumbar spinal segment, were made in the anaesthetised cat. The electrodes were positioned in cortical and spinal somatosensory regions where the largest spontaneous and evoked negative potentials were(More)
Stochastic resonance (SR) is commonly understood to be the enhancement, by noise, of the response of a system to a weak input signal. The aim of this study was to demonstrate the occurrence of SR in spinal and cortical evoked field potentials (EFPs) elicited by periodic tactile stimuli in the anesthetized cat. The electrodes were positioned in spinal and(More)
Harper [D.W. Harper, Signal detection analysis of effect of white noise intensity on sensitivity to visual flicker, Percept. Mot. Skills 48 (1979) 791-798] demonstrated that the visual flicker sensitivity was an inverted U-like function of the intensity of different levels of auditory noise from 50 to 90dB (SPL), without concomitant changes in the response(More)
Women with a family history of breast cancer (FHBC) are at increased risk for developing this disease. In this study, we have investigated the differences between two groups of women; those with family history of breast cancer (N=42) and women at population risk (N=42) in a Spanish cohort. Questionnaires assessed distress, perception of breast cancer risk,(More)
A previous study has shown that lumbar spontaneous cord dorsum potentials (CDPs) are produced by background activity of a neuronal ensemble located in the dorsal horn. Here, the effects produced by intravenous application of the nitric oxide synthase inhibitor L-N(G)-nitro arginine (L-NOARG, 100 microg/kg) and of the nitric oxide donor(More)
INTRODUCTION AND OBJECTIVES A cost-effectiveness model was developed to evaluate the efficiency of different preventive strategies in familial hypercholesterolemia (FH) in comparison with routine clinical practice (CP): atorvastatin monotherapy, 40 mg (A40) or 80 mg (A80, and atorvastatin combined with ezetimibe, 10 mg (A40+E10 or A80+E10). METHODS A(More)
Current working conditions and new forms of work organization are affecting workers' health in numerous ways which can only be explained by more complex theories and methodologies than those used traditionally. The authors analyze some important elements of the work process and the interaction among work demands as determinants of mental and psychosomatic(More)